17O NMR studies of organic and biological molecules in aqueous solution and in the solid state

G Wu - Progress in Nuclear Magnetic Resonance …, 2019 - Elsevier
This review describes the latest developments in the field of 17 O NMR spectroscopy of
organic and biological molecules both in aqueous solution and in the solid state. In the first …

Solid-state 17O NMR studies of organic and biological molecules: recent advances and future directions

G Wu - Solid state nuclear magnetic resonance, 2016 - Elsevier
This Trends article highlights the recent advances published between 2012 and 2015 in
solid-state 17 O NMR for organic and biological molecules. New developments in the …

[HTML][HTML] Algal ciguatoxin identified as source of ciguatera poisoning in the Caribbean

EM Mudge, CO Miles, L Ivanova, S Uhlig, KS James… - Chemosphere, 2023 - Elsevier
Ciguatera poisoning (CP) is a severe seafood-borne disease, caused by the consumption of
reef fish contaminated with Caribbean ciguatoxins (C-CTXs) in the Caribbean and tropical …

Probing O–H Bonding through Proton Detected 1H–17O Double Resonance Solid-State NMR Spectroscopy

SL Carnahan, BJ Lampkin, P Naik… - Journal of the …, 2018 - ACS Publications
The ubiquity of oxygen in organic, inorganic, and biological systems has stimulated the
application and development of 17O solid-state NMR spectroscopy as a probe of molecular …

17O MAS NMR Correlation Spectroscopy at High Magnetic Fields

EG Keeler, VK Michaelis, MT Colvin… - Journal of the …, 2017 - ACS Publications
The structure of two protected amino acids, FMOC-l-leucine and FMOC-l-valine, and a
dipeptide, N-acetyl-l-valyl-l-leucine (N-Ac-VL), were studied via one-and two-dimensional …

Ex Situ Generation of 18O2 and 17O2 from Endoperoxides for *O-Labeling and Mechanistic Studies of Oxidations by Dioxygen

A Doussot, MF Bakaï, E Fouquet, P Hermange - Organic Letters, 2023 - ACS Publications
Near-stoichiometric amounts of 18O2 and 17O2 were generated ex situ from endoperoxides
in a two-chamber glassware to oxidize various substrates. This strategy gave [* O2] …

Production and stability of oxygen-18 labeled Caribbean ciguatoxins and gambierones

EM Mudge, J Meija, S Uhlig, A Robertson, P McCarron… - Toxicon, 2022 - Elsevier
Ciguatoxins (CTXs) and gambierones are ladder-shaped polyethers associated with
ciguatera poisoning and Gambierdiscus spp. Several of these compounds contain carbonyl …

Catalytic Highly Regioselective C–H Oxygenation Using Water as the Oxygen Source: Preparation of 17O/18O-Isotope-Labeled Compounds

D Doiuchi, T Uchida - Organic letters, 2021 - ACS Publications
We found that the oxygen atom of water is activated to iodosylbenzene derivatives via
reversible hydrolysis of PhI (OOCR) 2 and can be used to the oxygen source for ruthenium …

Fast and Cost‐Efficient 17O‐Isotopic Labeling of Carboxylic Groups in Biomolecules: From Free Amino Acids to Peptide Chains

J Špačková, I Goldberga, R Yadav… - … A European Journal, 2023 - Wiley Online Library
Abstract 17O NMR spectroscopy is a powerful technique, which can provide unique
information regarding the structure and reactivity of biomolecules. However, the low natural …

Development of Catalytic Site‐Selective C− H Oxidation

T Uchida - The Chemical Record, 2023 - Wiley Online Library
Direct C− H bond oxygenation is a strong and useful tool for the construction of oxygen
functional groups. After Chen and White's pioneering works, various non‐heme‐type iron …