The development of asymmetric Michael additions for carbon–carbon bond formation is an
important challenge in organic synthesis. 1–5 These reactions have been performed under …

Cleavage of the N-(1-phenylethyl) unit of carboxamides using less than 1equiv of MsOH in
refluxing toluene was found to be simple and very efficient leading to the desired amides in …

Asymmetric Michael reaction: novel efficient access to chiral β-ketophosphonates -
ScienceDirect Skip to main contentSkip to article Elsevier logo Journals & Books Search …

In contrast with keto diester (R)-10a bearing a methyl ester group at the quaternary carbon
center, the benzyl ester analogue (R)-10a partially racemized during workup, thereby …

The effect of a fluorine atom on the asymmetric Michael reaction between a chiral α-fluoro-β-
enaminoester derived from (S)-1-phenylethylamine and various electrophilic alkenes is …

An efficient procedure to prepare chiral β-enamino esters by reaction of methyl propiolate
with chiral amines is described. Aza-annulation of these chiral β-enamino esters with …

Asymmetric Michael addition of chiral 2-fluoroenaminoesters derived from (S)-1-
phenylethylamine to α-substituted methyl acrylate leads to diastereomeric γ-substituted γ …

Acylation of methyl 3-aminocrotonate 1a in benzene with a variety of aliphatic and aromatic
acid chlorides including α, β-unsaturated acid chloride in the presence of an added organic …

Analogs of glutamic acid were synthesized through the asymmetric Michael reaction using
chiral acyclic E-enaminoesters and various Michael acceptors. The influence of the alkoxy …

Summary This Chapter Contains Sections titled: Reviews Electrophilic Additions
Halogenation and Related Reactions (i) Bromine (ii) Chlorine (ii) Iodine (iv) Fluorine …