[HTML][HTML] Benzodiazepines in the management of seizures and status epilepticus: a review of routes of delivery, pharmacokinetics, efficacy, and tolerability
R Kienitz, L Kay, I Beuchat, S Gelhard… - CNS drugs, 2022 - Springer
Status epilepticus (SE) is an acute, life-threatening medical condition that requires
immediate, effective therapy. Therefore, the acute care of prolonged seizures and SE is a …
immediate, effective therapy. Therefore, the acute care of prolonged seizures and SE is a …
Guidelines for the evaluation and management of status epilepticus
Status epilepticus (SE) treatment strategies vary substantially from one institution to another
due to the lack of data to support one treatment over another. To provide guidance for the …
due to the lack of data to support one treatment over another. To provide guidance for the …
Evidence-based guideline: treatment of convulsive status epilepticus in children and adults: report of the Guideline Committee of the American Epilepsy Society
T Glauser, S Shinnar, D Gloss, B Alldredge… - Epilepsy …, 2016 - journals.sagepub.com
CONTEXT: The optimal pharmacologic treatment for early convulsive status epilepticus is
unclear. OBJECTIVE: To analyze efficacy, tolerability and safety data for anticonvulsant …
unclear. OBJECTIVE: To analyze efficacy, tolerability and safety data for anticonvulsant …
[HTML][HTML] A comparison of four treatments for generalized convulsive status epilepticus
DM Treiman, PD Meyers, NY Walton… - … England Journal of …, 1998 - Mass Medical Soc
Background and Methods Although generalized convulsive status epilepticus is a life-
threatening emergency, the best initial drug treatment is uncertain. We conducted a five-year …
threatening emergency, the best initial drug treatment is uncertain. We conducted a five-year …
Why won't it stop? The dynamics of benzodiazepine resistance in status epilepticus
Status epilepticus is a life-threatening neurological emergency that affects both adults and
children. Approximately 36% of episodes of status epilepticus do not respond to the current …
children. Approximately 36% of episodes of status epilepticus do not respond to the current …
Benzodiazepines in epilepsy: pharmacology and pharmacokinetics
J Riss, J Cloyd, J Gates, S Collins - Acta neurologica …, 2008 - Wiley Online Library
Benzodiazepines (BZDs) remain important agents in the management of epilepsy. They are
drugs of first choice for status epilepticus and seizures associated with post‐anoxic insult …
drugs of first choice for status epilepticus and seizures associated with post‐anoxic insult …
[HTML][HTML] Pharmacotherapy for status epilepticus
Status epilepticus (SE) represents the most severe form of epilepsy. It is one of the most
common neurologic emergencies, with an incidence of up to 61 per 100,000 per year and …
common neurologic emergencies, with an incidence of up to 61 per 100,000 per year and …
Guidelines for the diagnosis and treatment of acute encephalopathy in childhood
The cardinal symptom of acute encephalopathy is impairment of consciousness of acute
onset during the course of an infectious disease, with duration and severity meeting defined …
onset during the course of an infectious disease, with duration and severity meeting defined …
Safety and efficacy of buccal midazolam versus rectal diazepam for emergency treatment of seizures in children: a randomised controlled trial
J McIntyre, S Robertson, E Norris, R Appleton… - The Lancet, 2005 - thelancet.com
Background Rectal diazepam and buccal midazolam are used for emergency treatment of
acute febrile and afebrile (epileptic) seizures in children. We aimed to compare the safety …
acute febrile and afebrile (epileptic) seizures in children. We aimed to compare the safety …
[HTML][HTML] The relative effectiveness of five antiepileptic drugs in treatment of benzodiazepine-resistant convulsive status epilepticus: a meta-analysis of published …
Z Yasiry, SD Shorvon - Seizure, 2014 - Elsevier
Purpose Systematic evaluation of published evidence-base of the efficacy of five
antiepileptic drugs–lacosamide, levetiracetam, valproate, phenytoin and phenobarbital–in …
antiepileptic drugs–lacosamide, levetiracetam, valproate, phenytoin and phenobarbital–in …