Gastric cancer (GC) is a complex and heterogeneous disease with significant phenotypic
and genetic variation. Traditional classification systems rely mainly on the evaluation of …

Objective An international meeting was organised to develop consensus on (1) the
landmarks to define the gastro-oesophageal junction (GOJ),(2) the occurrence and …

Background The incidence of esophageal adenocarcinoma (EAC) is rapidly rising and has a
5-year survival rate of< 20%. Beyond TNM (tumor–node–metastasis) staging, no reliable risk …

Objective: To investigate the molecular characteristics of AGEJ compared with EAC and
gastric adenocarcinoma. Summary of Background Data: Classification of AGEJ based on …

Chronic acid-biliary reflux and Helicobacter pylori infection are instrumental environmental
drivers of cancer initiation and progression in the upper gastrointestinal tract. Remarkably …

Objective Prognosis of patients with advanced oesophagogastric adenocarcinoma
(mEGAC) is poor and molecular determinants of shorter or longer overall survivors are …

Simple Summary Esophageal and esophago-gastric junction adenocarcinomas (EA/EGJAs)
are a heterogeneous group of cancers. Stage is the most important prognostic factor, while …

The incidence of adenocarcinoma of the esophagogastric junction (AEG) has markedly
increased worldwide. However, the precise etiology of AEG is still unclear, and the …

Gastric adenocarcinoma (GAC) is the most frequent type of stomach cancer, characterized
by high heterogeneity and phenotypic diversity. Although many novel strategies have been …

Simple Summary Esophageal adenocarcinoma (EAC) is one of the two major subtypes of
esophageal cancer. In early disease stage, many EAC patients are asymptomatic. Most …