Genomes are self-organized and self-maintained as long, complex macromolecules of
chromatin. The inherent heterogeneity, stochasticity, phase separation, and chromatin …

RAD51 recombinase plays a central role in homologous recombination (HR) by forming a
nucleoprotein filament on single-stranded DNA (ssDNA) to catalyze homology search and …

RAD54 family DNA translocases partner with RAD51 recombinases to ensure stable
genome inheritance, exhibiting biochemical activities both in promoting recombinase …

Rdh54 is a conserved DNA translocase that participates in homologous recombination (HR),
DNA checkpoint adaptation, and chromosome segregation. Saccharomyces cerevisiae …

Abstract Multiple eukaryotic SWI2/SNF2 DNA translocases safeguard genome integrity,
mostly by remodelling nucleosomes, but also by fine-tuning mechanisms of DNA repair …

Homologous recombination (HR) is a template-based DNA double-strand break repair
pathway that functions to maintain genomic integrity. A vital component of the HR reaction is …

The proper maintenance of genetic material is essential for the survival of living organisms.
One of the main safeguards of genome stability is homologous recombination involved in …

Homologous recombination (HR) is a double-strand break DNA repair pathway that
preserves chromosome structure. To repair damaged DNA, HR uses an intact donor DNA …

In many eukaryotes, including both budding yeast and mammals, repair of double-strand
breaks (DSBs) is carried out by different apparatus in somatic and meiotic cells. In mitotic …

L'usage de composé chimique causant des dommages à l'ADN en phase S est une
stratégie couramment utilisée en chimiothérapie du cancer. Ainsi, l'étude de la réponse …