Pathogenesis and management of traumatic brain injury (TBI): role of neuroinflammation and anti-inflammatory drugs

S Kalra, R Malik, G Singh, S Bhatia, A Al-Harrasi… - …, 2022 - Springer
Traumatic brain injury (TBI) is an important global health concern that represents a leading
cause of death and disability. It occurs due to direct impact or hit on the head caused by …

A systematic review of closed head injury models of mild traumatic brain injury in mice and rats

CN Bodnar, KN Roberts, EK Higgins… - Journal of …, 2019 - liebertpub.com
Mild TBI (mTBI) is a significant health concern. Animal models of mTBI are essential for
understanding mechanisms, and pathological outcomes, as well as to test therapeutic …

Fipronil insecticide toxicology: oxidative stress and metabolism

X Wang, MA Martínez, Q Wu, I Ares… - Critical reviews in …, 2016 - Taylor & Francis
Fipronil (FIP) is widely used across the world as a broad-spectrum phenylpyrazole
insecticide and veterinary drug. FIP was the insecticide to act by targeting the γ-aminobutyric …

Brain neurotrauma: molecular, neuropsychological, and rehabilitation aspects

FH Kobeissy - 2015 - books.google.com
With the contribution from more than one hundred CNS neurotrauma experts, this book
provides a comprehensive and up-to-date account on the latest developments in the area of …

Treatment of traumatic brain injury with anti-inflammatory drugs

PJ Bergold - Experimental neurology, 2016 - Elsevier
Traumatic brain injury rapidly induces inflammation. This inflammation is produced both by
endogenous brain cells and circulating inflammatory cells that enter from the brain. Together …

Management of traumatic brain injury: from present to future

R Crupi, M Cordaro, S Cuzzocrea, D Impellizzeri - Antioxidants, 2020 - mdpi.com
TBI (traumatic brain injury) is a major cause of death among youth in industrialized societies.
Brain damage following traumatic injury is a result of direct and indirect mechanisms; …

Blood–brain barrier dysfunction following traumatic brain injury

H Alluri, K Wiggins-Dohlvik, ML Davis, JH Huang… - Metabolic brain …, 2015 - Springer
Traumatic brain injury is a serious cause of morbidity and mortality worldwide. After
traumatic brain injury, the blood–brain barrier, the protective barrier between the brain and …

Therapies targeting lipid peroxidation in traumatic brain injury

TS Anthonymuthu, EM Kenny, H Bayır - Brain research, 2016 - Elsevier
Lipid peroxidation can be broadly defined as the process of inserting a hydroperoxy group
into a lipid. Polyunsaturated fatty acids present in the phospholipids are often the targets for …

Poldip2 mediates blood-brain barrier disruption in a model of sepsis-associated encephalopathy

DS Kikuchi, ACP Campos, H Qu, SJ Forrester… - Journal of …, 2019 - Springer
Background Sepsis-associated encephalopathy (SAE), a diffuse cerebral dysfunction in the
absence of direct CNS infection, is associated with increased rates of mortality and morbidity …

Methamphetamine effects on blood-brain barrier structure and function

NA Northrop, BK Yamamoto - Frontiers in neuroscience, 2015 - frontiersin.org
Methamphetamine (Meth) is a widely abuse psychostimulant. Traditionally, studies have
focused on the neurotoxic effects of Meth on monoaminergic neurotransmitter terminals …