Epithelial–mesenchymal transition (EMT) encompasses dynamic changes in cellular
organization from epithelial to mesenchymal phenotypes, which leads to functional changes …

Epithelial–mesenchymal plasticity (EMP) enables cells to interconvert between several
states across the epithelial–mesenchymal landscape, thereby acquiring hybrid epithelial …

Renal fibrosis is the final pathological process common to any ongoing, chronic kidney
injury or maladaptive repair. It is considered as the underlying pathological process of …

Kidney fibrosis is marked by an epithelial-to-mesenchymal transition (EMT) of tubular
epithelial cells (TECs). Here we find that, during renal fibrosis, TECs acquire a partial EMT …

Diabetic kidney disease (DKD), as the most common complication of diabetes mellitus (DM),
is the major cause of end-stage renal disease (ESRD). Renal interstitial fibrosis is a crucial …

Fibrosis is a chronic and progressive disorder characterized by excessive deposition of
extracellular matrix, which leads to scarring and loss of function of the affected organ or …

Somatic cells that change from one mature phenotype to another exhibit the property of
plasticity. It is increasingly clear that epithelial and endothelial cells enjoy some of this …

The pathologic paradigm for renal progression is advancing tubulointerstitial fibrosis.
Whereas mechanisms underlying fibrogenesis have grown in scope and understanding in …

Epithelial-to-mesenchymal transition (EMT) is a self-regulated physiological process
required for tissue repair that, in non-controled conditions may lead to fibrosis …

Abstract Epithelial-mesenchymal transition (EMT), a process by which differentiated
epithelial cells undergo a phenotypic conversion that gives rise to the matrix-producing …