For a century, since the pioneering work of Otto Warburg, the interwoven relationship
between metabolism and cancer has been appreciated. More recently, with obesity rates …

O-GlcNAcylation is a post-translational modification occurring on serine/threonine residues
of nuclear and cytoplasmic proteins, mediated by the enzymes OGT and OGA which …

For decades, great strides have been made in the field of immunometabolism. A plethora of
evidence ranging from basic mechanisms to clinical transformation has gradually embarked …

Abstract O-linked-N-acetylglucosaminylation (O-GlcNAcylation), a dynamic post-
translational modification (PTM), holds profound implications in controlling various cellular …

Women with obesity who develop breast cancer have a worsened prognosis with
diminished survival rates and increased rates of metastasis. Obesity is also associated with …

Diabetes commonly affects patients with cancer. We investigated the influence of diabetes
on breast cancer biology using a 3-pronged approach that included analysis of orthotopic …

Increasing evidence highlights approaches targeting metabolism as potential adjuvants to
cancer therapy. Sodium-glucose transport protein 2 (SGLT2) inhibitors are the newest class …

Simple Summary Cervical cancer is the most commonly diagnosed gynecological malignant
carcinoma worldwide. It is crucial to develop reliable prognostic models to predict clinical …

Hemostatic materials are generally applied in surgical operations for cancer, but their effects
on the growth and recurrence of tumors are unclear. Herein, three commonly used naturally …

Background Lack of adequate objectivity and universality, available models are still difficult
to be applied to clinical practice in predicting occult cervical metastasis of early oral …