Cardiovascular and renal outcomes with SGLT-2 inhibitors versus GLP-1 receptor agonists in patients with type 2 diabetes mellitus and chronic kidney disease: a …

T Yamada, M Wakabayashi, A Bhalla, N Chopra… - Cardiovascular …, 2021 - Springer
Background Emerging evidence suggests that sodium-glucose cotransporter-2 (SGLT-2)
inhibitors and glucagon-like peptide-1 receptor agonists (GLP-1 RAs) are associated with …

Can metformin exert as an active drug on endothelial dysfunction in diabetic subjects?

T Salvatore, PC Pafundi, R Galiero, L Rinaldi… - Biomedicines, 2020 - mdpi.com
Cardiovascular mortality is a major cause of death among in type 2 diabetes (T2DM).
Endothelial dysfunction (ED) is a well-known important risk factor for the development of …

Modifiable risk factors in young adults with first myocardial infarction

S Yandrapalli, C Nabors, A Goyal, WS Aronow… - Journal of the American …, 2019 - jacc.org
Abstract Background: Modifiable risk factors (RFs) play an important role in the development
and prognosis of acute myocardial infarction (AMI). Objectives: This study sought to study …

Wearable glucose monitoring and implantable drug delivery systems for diabetes management

J Zhang, J Xu, J Lim, JK Nolan, H Lee… - Advanced Healthcare …, 2021 - Wiley Online Library
The global cost of diabetes care exceeds 1trillioneachyearwithmorethan 327 billion being
spent in the United States alone. Despite some of the advances in diabetes care including …

Trends in first-line glucose-lowering drug use in adults with type 2 diabetes in light of emerging evidence for SGLT-2i and GLP-1RA

HJ Shin, S Schneeweiss, RJ Glynn, E Patorno - Diabetes Care, 2021 - Am Diabetes Assoc
OBJECTIVE We evaluated recent use trends and predictors of first-line antidiabetes
treatment in patients with type 2 diabetes. RESEARCH DESIGN AND METHODS Using two …

Cardiovascular and kidney outcomes of combination therapy with sodium-glucose cotransporter-2 inhibitors and mineralocorticoid receptor antagonists in patients …

S Tsukamoto, R Morita, T Yamada, S Urate… - Diabetes Research and …, 2022 - Elsevier
Aims Both sodium-glucose cotransporter-2 (SGLT-2) inhibitors and mineralocorticoid
receptor antagonists (MRAs) have been shown to reduce cardiovascular (CV) event in …

Why the endothelium? The endothelium as a target to reduce diabetes-associated vascular disease

CR Triggle, H Ding, I Marei, TJ Anderson… - Canadian journal of …, 2020 - cdnsciencepub.com
Over the past 66 years, our knowledge of the role of the endothelium in the regulation of
cardiovascular function and dysfunction has advanced from the assumption that it is a single …

Empagliflozin prohibits high-fructose diet-induced cardiac dysfunction in rats via attenuation of mitochondria-driven oxidative stress

P Bugga, SA Mohammed, MJ Alam, P Katare… - Life Sciences, 2022 - Elsevier
SGLT2 inhibitors show promising cardio-protection in the diabetic populace. However, the
defending effect of SGLT2 inhibition in diabetes-associated cardiac complications and the …

[HTML][HTML] Nutritional, phytochemical, antioxidant, α-glucosidase and α-amylase inhibitory properties of Moringa oleifera seeds

X Gu, Y Yang, Z Wang - South African Journal of Botany, 2020 - Elsevier
The aim of this study was to analyze nutritional characteristics of Moringa oleifera seed and
evaluate phytochemical compounds, as well as antioxidant and enzyme inhibitory activities …

Adjuvant therapy with mushroom polysaccharides for diabetic complications

X Jiang, W Meng, L Li, Z Meng, D Wang - Frontiers in Pharmacology, 2020 - frontiersin.org
Background Diabetic complications seriously endanger the health of most diabetic patients
around the world. Most chemical hypoglycemic agents have adverse effects and are unable …