Plumbing mysterious RNAs in “dark genome” for the conquest of human diseases

LA Huang, C Lin, L Yang - Molecular Therapy, 2023 - cell.com
Next-generation sequencing has revealed that less than 2% of transcribed genes are
translated into proteins, with a large portion transcribed into noncoding RNAs (ncRNAs) …

Interrelated grid of non-coding RNA: An important aspect in Rheumatoid Arthritis pathogenesis

M Saquib, P Agnihotri, Monu, S Biswas - Molecular Biology Reports, 2023 - Springer
Inflammation and autoimmunity are the root cause of rheumatoid arthritis, a destructive
disease of joints. Multiple biomolecules are involved in the pathogenesis of RA and are …

Deciphering the role of circulating lncRNAs: RNCR2, NEAT2, CDKN2B-AS1, and PVT1 and the possible prediction of anti-VEGF treatment outcomes in diabetic …

EA Toraih, AA Abdelghany, NM Abd El Fadeal… - Graefe's Archive for …, 2019 - Springer
Purpose Putative roles of long non-coding RNAs (lncRNAs) as indicators for diabetic
retinopathy (DR) and associated complications are beginning to emerge. We aimed to …

Transcriptome-wide profiling of cerebral cavernous malformations patients reveal important long noncoding RNA molecular signatures

S Subhash, N Kalmbach, F Wegner, S Petri, T Glomb… - Scientific reports, 2019 - nature.com
Cerebral cavernous malformations (CCMs) are low-flow vascular malformations in the brain
associated with recurrent hemorrhage and seizures. The current treatment of CCMs relies …

Differential lncRNA expression profiling of cognitive function in middle and old aged monozygotic twins using generalized association analysis

A Mohammadnejad, J Baumbach, W Li, J Lund… - Journal of Psychiatric …, 2021 - Elsevier
Cognitive impairment is the most prominent symptom in neurodegenerative disorders
affecting quality of life and mortality. However, despite years of research, the molecular …

Three novel antisense overlapping genes in E. coli O157: H7 EDL933

F Graf, B Zehentner, L Fellner, S Scherer… - Microbiology …, 2023 - Am Soc Microbiol
The abundance of long overlapping genes in prokaryotic genomes is likely to be
significantly underestimated. To date, only a few examples of such genes are fully …