The triangle relationship between long noncoding RNA, RIG-I-like receptor signaling pathway, and glycolysis

Z Ren, Y Yu, C Chen, D Yang, T Ding, L Zhu… - Frontiers in …, 2021 - frontiersin.org
Long noncoding RNA (LncRNA), a noncoding RNA over 200nt in length, can regulate
glycolysis through metabolic pathways, glucose metabolizing enzymes, and epigenetic …

African swine fever virus and host response: transcriptome profiling of the Georgia 2007/1 strain and porcine macrophages

G Cackett, R Portugal, D Matelska, L Dixon… - Journal of …, 2022 - Am Soc Microbiol
African swine fever virus (ASFV) has a major global economic impact. With a case fatality in
domestic pigs approaching 100%, it currently presents the largest threat to animal farming …

Effects of the NF-κB signaling pathway inhibitor BAY11-7082 in the replication of ASFV

Q Gao, Y Yang, Y Feng, W Quan, Y Luo, H Wang… - Viruses, 2022 - mdpi.com
African swine fever virus (ASFV) mainly infects the monocyte/macrophage lineage of pigs
and regulates the production of cytokines that influence host immune responses. Several …

Transcriptome profiling reveals features of immune response and metabolism of acutely infected, dead and asymptomatic infection of African swine fever virus in pigs

H Sun, Q Niu, J Yang, Y Zhao, Z Tian, J Fan… - Frontiers in …, 2021 - frontiersin.org
African swine fever virus (ASFV) infection can result in lethal disease in pigs. ASFV encodes
150-167 proteins, of which only approximately 50 encoded viral structure proteins are …

African swine fever virus infection activates inflammatory responses through downregulation of the anti-inflammatory molecule C1QTNF3

C Lv, Q Zhang, L Zhao, J Yang, Z Zou, Y Zhao… - Frontiers in …, 2022 - frontiersin.org
African swine fever (ASF) is the most dangerous pig disease, and causes enormous
economic losses in the global pig industry. However, the mechanisms of ASF virus (ASFV) …

Infection characteristics and transcriptomics of African swine fever virus in Bama minipigs

C Lv, J Yang, L Zhao, C Wu, C Kang… - Microbiology …, 2022 - Am Soc Microbiol
Animal experiments on African swine fever virus (ASFV) are vital to the study of ASFV;
however, ASFV can only infect pigs, and animal experiments need to be performed in …

Rapid conversion of porcine pluripotent stem cells into macrophages with chemically defined conditions

X Wu, Y Ni, W Li, B Yang, X Yang, Z Zhu… - Journal of Biological …, 2024 - ASBMB
A renewable source of porcine macrophages derived from pluripotent stem cells (PSCs)
would be a valuable alternative to primary porcine alveolar macrophages (PAMs) in the …

Identification of African swine fever virus transcription within peripheral blood mononuclear cells of acutely infected pigs

AS Olesen, M Kodama, L Lohse, F Accensi… - Viruses, 2021 - mdpi.com
African swine fever virus (ASFV) has become widespread in Europe, Asia and elsewhere,
thereby causing extensive economic losses. The viral genome includes nearly 200 genes …

Targeted editing of susceptibility genes for plant disease resistance: Current state and future hopes

LU Rani, M Shelke, M Sandhya, G Senthilraja - Plant Gene, 2024 - Elsevier
Plants are constantly exposed to a plethora of pathogens including bacteria, fungi, and
viruses posing significant challenges to global food security. The susceptibility of plants to …

K205R specific nanobody-horseradish peroxidase fusions as reagents of competitive ELISA to detect African swine fever virus serum antibodies

A Zhang, S Wu, X Duan, H Zhao, H Dong, J Ren… - BMC Veterinary …, 2022 - Springer
Background African swine fever virus (ASFV) is a highly contagious hemorrhagic disease
and often lethal, which has significant economic consequences for the swine industry. Due …