Infections are the most common and significant cause of mortality and morbidity after
allogeneic hematopoietic stem cell transplantation (allo-HSCT). The presence of …

Extragonadal germ cell tumors (GCTs) are relatively uncommon, but represent 1% to 5% of
all GCTs. Their morphology varies widely and includes mature teratoma, immature teratoma …

Testicular cancer is the most frequent tumor in young males aged 15–39 years. As cure
rates are currently around 90%, the prevalence of survivors is increasing. However, a …

Maintenance of ex vivo hematopoietic stem cells (HSC) pool and its differentiated progeny is
regulated by complex network of transcriptional factors, cell cycle proteins, extracellular …

Background Allogeneic hematopoietic stem cell transplantation from haploidentical donor is
a feasible option for patients with hematological diseases who lack a suitable HLA-matched …

Background Although the survival of children and adolescents with malignant germ-cell
tumours has improved greatly in recent years, the outcome remains poor for those with …

The following is a general overview of the management of CNS germinomas. Over the last
35 years, CNS germinomas have become one of the pediatric brain tumors with the best …

Allogeneic hematopoietic stem cell transplantation (Allo-HSCT) is a curative treatment
option for both malignant and some benign hematological diseases. During the last decade …

Iron overload is an adverse prognostic factor for patients undergoing hematopoietic stem
cell transplantation (HSCT). In the HSCT setting, pretransplant and early posttransplant …

Stem cells can be either totipotent, pluripotent, multipotent or unipotent. Totipotent cells have
the capability to produce all cell types of the developing organism, including both embryonic …