Congenital transmission of apicomplexan parasites: a review

M Rojas-Pirela, L Medina, MV Rojas… - Frontiers in …, 2021 - frontiersin.org
Apicomplexans are a group of pathogenic protists that cause various diseases in humans
and animals that cause economic losses worldwide. These unicellular eukaryotes are …

[HTML][HTML] Toxoplasma gondii secretory proteins and their role in invasion and pathogenesis

Y Zhang, BS Lai, M Juhas, Y Zhang - Microbiological research, 2019 - Elsevier
T. gondii is a major opportunistic pathogen chronically infecting nearly one third of the
world's population. Due to the high infection and mortality rates in immunocompromised …

Harnessing human papillomavirus' natural tropism to target tumors

RC Kines, JT Schiller - Viruses, 2022 - mdpi.com
Human papillomaviruses (HPV) are small non-enveloped DNA tumor viruses established as
the primary etiological agent for the development of cervical cancer. Decades of research …

Antiparasitic effects of sulfated polysaccharides from marine hydrobionts

NN Besednova, TS Zaporozhets, BG Andryukov… - Marine Drugs, 2021 - mdpi.com
This review presents materials characterizing sulfated polysaccharides (SPS) of marine
hydrobionts (algae and invertebrates) as potential means for the prevention and treatment of …

Cell invasion by intracellular parasites–the many roads to infection

MF Horta, LO Andrade… - Journal of cell …, 2020 - journals.biologists.com
Intracellular parasites from the genera Toxoplasma, Plasmodium, Trypanosoma,
Leishmania and from the phylum Microsporidia are, respectively, the causative agents of …

Transcriptional signatures of clonally derived Toxoplasma tachyzoites reveal novel insights into the expression of a family of surface proteins

TC Theisen, JC Boothroyd - PLoS One, 2022 - journals.plos.org
Toxoplasma gondii has numerous, large, paralogous gene families that are likely critical for
supporting its unparalleled host range: nearly any nucleated cell in almost any warm …

Secreted Toxoplasma gondii molecules interfere with expression of MHC-II in interferon gamma-activated macrophages

LP Leroux, D Dasanayake, LM Rommereim… - International journal for …, 2015 - Elsevier
The obligate intracellular protozoan parasite Toxoplasma gondii interferes with major
histocompatibility complex class II antigen presentation to dampen host CD4+ T cell …

The Cryptosporidium parvum C-type lectin CpClec mediates infection of intestinal epithelial cells via interactions with sulfated proteoglycans

JG Ludington, HD Ward - Infection and Immunity, 2016 - Am Soc Microbiol
The apicomplexan parasite Cryptosporidium causes significant diarrheal disease
worldwide. Effective anticryptosporidial agents are lacking, in part because the molecular …

Unravelling strain-specific modifications of Toxoplasma gondii tRNA and sncRNA using LC-MS/MS

W Wang, Y Yang, H Guo, MH Li, XQ Chen… - Microbiology …, 2023 - Am Soc Microbiol
Many RNA modifications have been detected in rRNA, tRNA and small noncoding RNA
(sncRNA) as well as in low-abundance RNA species such mRNA. Although RNA …

Requirement of microtubules for secretion of a micronemal protein CpTSP4 in the invasive stage of the apicomplexan Cryptosporidium parvum

D Wang, P Jiang, X Wu, Y Zhang, C Wang, M Li, M Liu… - Mbio, 2024 - Am Soc Microbiol
The zoonotic Cryptosporidium parvum is a global contributor to infantile diarrheal diseases
and opportunistic infections in immunocompromised or weakened individuals. Like other …