Blood pressure lowering efficacy of angiotensin converting enzyme (ACE) inhibitors for primary hypertension

BS Heran, MMY Wong, IK Heran… - Cochrane Database of …, 2008 - cochranelibrary.com
Background ACE inhibitors are widely prescribed for hypertension so it is essential to
determine and compare their effects on blood pressure (BP), heart rate and withdrawals due …

Serotonin and serotonin antagonism in cardiovascular and non‐cardiovascular disease

WH Frishman, S Huberfeld, S Okin… - The Journal of …, 1995 - Wiley Online Library
Serotonin, or 5‐hydroxytryptamine, is a naturally‐occurring vasoactive substance found
primarily in the brain, enterochromaffin tissue, and blood platelets. It has diffuse …

[HTML][HTML] Ketanserin: a review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in hypertension and peripheral vascular disease

RN Brogden, EM Sorkin - Drugs, 1990 - Springer
Ketanserin is a 5-HT 2 receptor antagonist without partial agonist properties which also
possesses weak α 1-adrenoceptor antagonistic activity, which may explain its …

Formulation for the prevention of cardiovascular disease

NJ Wald, MR Law - US Patent 8,470,868, 2013 - Google Patents
This invention relates to a method for the prevention of cardiovascular disease, a formulation
for the prevention of cardiovascular disease, the use of specified active principals for the …

Formulation for the prevention of cardiovascular disease

NJ Wald, MR Law - US Patent 10,357,503, 2019 - Google Patents
This invention relates to a method for the prevention of cardiovascular disease, a formulation
for the prevention of cardiovascular disease, the use of specified active principals for the …

Role of ACE inhibitors in uncomplicated essential hypertension

JIS Robertson - British heart journal, 1994 - ncbi.nlm.nih.gov
The design and early development of drugs which inhibited angiotensin converting enzyme
(ACE inhibitors) was conducted with the expectation that the principal applications of such …

Ketanserin alone and in combination with enalapril in the treatment of essential hypertension: assessment of the haemodynamic effects

O De Divitiis, M Galderisi, A Celentano… - Journal of …, 1993 - journals.sagepub.com
The antihypertensive and haemodynamic efficacies of ketanserin and ketanserin plus
enalapril were compared. The monotherapy phase of the study involved the oral …