Pathogenesis of the Pseudomonas aeruginosa Biofilm: A Review

FF Tuon, LR Dantas, PH Suss, VS Tasca Ribeiro - Pathogens, 2022 - mdpi.com
Pseudomonas aeruginosa is associated with several human infections, mainly related to
healthcare services. In the hospital, it is associated with resistance to several antibiotics …

Regulatory mechanisms and promising applications of quorum sensing-inhibiting agents in control of bacterial biofilm formation

L Zhou, Y Zhang, Y Ge, X Zhu, J Pan - Frontiers in microbiology, 2020 - frontiersin.org
A biofilm is an assemblage of microbial cells attached to a surface and encapsulated in an
extracellular polymeric substance (EPS) matrix. The formation of a biofilm is one of the …

Quorum sensing: a prospective therapeutic target for bacterial diseases

Q Jiang, J Chen, C Yang, Y Yin… - BioMed Research …, 2019 - Wiley Online Library
Bacterial quorum sensing (QS) is a cell‐to‐cell communication in which specific signals are
activated to coordinate pathogenic behaviors and help bacteria acclimatize to the …

Pseudomonas aeruginosa Biofilms: Host Response and Clinical Implications in Lung Infections

NM Maurice, B Bedi, RT Sadikot - American journal of respiratory …, 2018 - atsjournals.org
Pseudomonas aeruginosa is a major health challenge that causes recalcitrant multidrug-
resistant infections, especially in immunocompromised and hospitalized patients. P …

The hierarchy quorum sensing network in Pseudomonas aeruginosa

J Lee, L Zhang - Protein & cell, 2015 - academic.oup.com
Pseudomonas aeruginosa causes severe and persistent infections in immune compromised
individuals and cystic fibrosis sufferers. The infection is hard to eradicate as P. aeruginosa …

Quorum sensing inhibitors as antipathogens: biotechnological applications

VC Kalia, SKS Patel, YC Kang, JK Lee - Biotechnology advances, 2019 - Elsevier
The mechanisms through which microbes communicate using signal molecules has inspired
a great deal of research. Microbes use this exchange of information, known as quorum …

Exploiting extracellular polymeric substances (EPS) controlling strategies for performance enhancement of biological wastewater treatments: an overview

Y Shi, J Huang, G Zeng, Y Gu, Y Chen, Y Hu, B Tang… - Chemosphere, 2017 - Elsevier
Extracellular polymeric substances (EPS) are present both outside of the cells and in the
interior of microbial aggregates, and account for a main component in microbial aggregates …

Quorum sensing inhibitors: an overview

VC Kalia - Biotechnology advances, 2013 - Elsevier
Excessive and indiscriminate use of antibiotics to treat bacterial infections has lead to the
emergence of multiple drug resistant strains. Most infectious diseases are caused by …

Exploiting quorum sensing to confuse bacterial pathogens

B LaSarre, MJ Federle - Microbiology and molecular biology …, 2013 - Am Soc Microbiol
Cell-cell communication, or quorum sensing, is a widespread phenomenon in bacteria that
is used to coordinate gene expression among local populations. Its use by bacterial …

Quorum quenching enzymes and their effects on virulence, biofilm, and microbiomes: a review of recent advances

R Sikdar, M Elias - Expert review of anti-infective therapy, 2020 - Taylor & Francis
Introduction Numerous bacterial behaviors are regulated by a cell-density dependent
mechanism known as Quorum Sensing (QS). QS relies on communication between bacterial …