Mechanistic insight into toxicity of phthalates, the involved receptors, and the role of Nrf2, NF-κB, and PI3K/AKT signaling pathways
H Mohammadi, S Ashari - Environmental Science and Pollution Research, 2021 - Springer
The wide use of phthalates, as phthalates are used in the manufacturing of not only plastics
but also many others goods, has become a main concern in the current century because of …
but also many others goods, has become a main concern in the current century because of …
The overview of current evidence on the reproductive toxicity of dibutyl phthalate
E Czubacka, S Czerczak… - International Journal of …, 2021 - ppm.imp.lodz.pl
Over the past years, many legitimate concerns have been raised about the effects of dibutyl
phthalate (DBP) as an endocrine disruptor, especially on reproduction. The aim of this …
phthalate (DBP) as an endocrine disruptor, especially on reproduction. The aim of this …
Gut microbiota may contribute to the postnatal male reproductive abnormalities induced by prenatal dibutyl phthalate exposure
T Zhang, X Zhou, X Zhang, X Ren, J Wu, Z Wang… - Chemosphere, 2022 - Elsevier
Phthalate is an environmental endocrine disruptor that causes direct and intergenerational
male reproductive damage. However, its mechanisms require further investigation. The role …
male reproductive damage. However, its mechanisms require further investigation. The role …
Exposure to an environmentally relevant phthalate mixture during prostate development induces microRNA upregulation and transcriptome modulation in rats
WR Scarano, A Bedrat, LG Alonso-Costa… - Toxicological …, 2019 - academic.oup.com
Environmental exposure to phthalates during intrauterine development might increase
susceptibility to neoplasms in reproductive organs such as the prostate. Although studies …
susceptibility to neoplasms in reproductive organs such as the prostate. Although studies …
[HTML][HTML] Phthalate metabolites concentrations in amniotic fluid and maternal urine: cumulative exposure and risk assessment
Phthalates are used in industry as plasticizers or additives in everyday products and they
have been considered as endocrine disrupting chemicals. Maternal exposure during …
have been considered as endocrine disrupting chemicals. Maternal exposure during …
Dibutyl phthalate contamination accelerates the uptake and metabolism of sugars by microbes in black soil
W Chen, Z Wang, W Xu, R Tian, J Zeng - Environmental pollution, 2020 - Elsevier
Dibutyl phthalate (DBP) is widely used as plasticizer and has been detected in the
environment, posing a threat to animal health. However, the effects of DBP on agricultural …
environment, posing a threat to animal health. However, the effects of DBP on agricultural …
Effects of a phthalate metabolite mixture on both normal and tumoral human prostate cells
Phthalates represent a group of substances used in industry that have antiandrogenic
activity and are found in different concentrations in human urine and plasma. More than 8 …
activity and are found in different concentrations in human urine and plasma. More than 8 …
Effects of Dibutylphthalate and Steroid Hormone Mixture on Human Prostate Cells
A Mileo, T Chianese, G Fasciolo, P Venditti… - International Journal of …, 2023 - mdpi.com
Phthalates are a family of aromatic chemical compounds mainly used as plasticizers. Among
phthalates, di-n-butyl phthalate (DBP) is a low-molecular-weight phthalate used as a …
phthalates, di-n-butyl phthalate (DBP) is a low-molecular-weight phthalate used as a …
Integrated transcriptome and proteome analysis indicates potential biomarkers of prostate cancer in offspring of pregnant rats exposed to a phthalate mixture during …
AM Aquino, LG Alonso-Costa, SAA Santos, VA Rocha… - Chemosphere, 2023 - Elsevier
As the second leading cause of death for cancer among men worldwide, prostate cancer
(PCa) prevention and detection remain a critical challenge. One aspect of PCa research is …
(PCa) prevention and detection remain a critical challenge. One aspect of PCa research is …
In silico investigation of the role of miRNAs in a possible developmental origin of prostate cancer in F1 and F2 offspring of mothers exposed to a phthalate mixture
AM Aquino, MN Fioretto… - Environmental …, 2024 - Wiley Online Library
A previous study using miRNA sequencing revealed that exposure to a mixture of phthalates
during pregnancy and lactation dysregulated rno‐miR‐184 and rno‐miR‐141‐3p in the …
during pregnancy and lactation dysregulated rno‐miR‐184 and rno‐miR‐141‐3p in the …