Traumatic brain injury (TBI) is the leading cause of morbidity and mortality worldwide.
Although TBI leads to mechanical damage during initial impact, secondary damage also …

Oxidative stress plays a crucial role in traumatic brain injury (TBI) pathogenesis. Reactive
oxygen species (ROS) and reactive nitrogen species (RNS) formed in excess after TBI …

There is an increasing evidence that inflammation contributes to clinical and functional
outcomes in traumatic brain injury (TBI). Many successful target-engaging, lesion-reducing …

Despite recent encouraging pharmaceutical and technical breakthroughs in neurosurgical
critical care, traumatic brain injury (TBI)-related mortality and morbidity remain substantial …

Introduction Accounting for 90% of all traumatic brain injuries (TBIs), mild traumatic brain
injury (mTBI) is currently the most frequently seen type of TBI. Although most patients can …

Background Statins have been shown to improve outcomes in traumatic brain injury (TBI) in
animal models. The aim of our study was to determine the effect of preinjury statins on …

A dysregulated host immune response significantly contributes to morbidity and mortality in
tuberculous meningitis (TBM). Effective host directed therapies (HDTs) are critical to improve …

Statins are well-tolerated and widely available lipid-lowering medications with
neuroprotective effects against traumatic brain injury (TBI). However, whether delayed statin …

BACKGROUND: Despite recent promising pharmacological and technological advances in
neurosurgical intensive care, the overall TBI-related mortality and morbidity remain high and …

Background Several in-vitro and animal studies suggest that statins may have beneficial
effects on clinical outcomes of traumatic brain injury (TBI), however, clinical data are scarce …