Shaping bacterial gene expression by physiological and proteome allocation constraints
M Scott, T Hwa - Nature Reviews Microbiology, 2023 - nature.com
Networks of molecular regulators are often the primary objects of focus in the study of gene
regulation, with the machinery of protein synthesis tacitly relegated to the background …
regulation, with the machinery of protein synthesis tacitly relegated to the background …
An ensemble approach to the structure-function problem in microbial communities
The metabolic activity of microbial communities plays a primary role in the flow of essential
nutrients throughout the biosphere. Molecular genetics has revealed the metabolic …
nutrients throughout the biosphere. Molecular genetics has revealed the metabolic …
Cell aggregation is associated with enzyme secretion strategies in marine polysaccharide-degrading bacteria
G D'Souza, A Ebrahimi, A Stubbusch… - The ISME …, 2023 - academic.oup.com
Polysaccharide breakdown by bacteria requires the activity of enzymes that degrade
polymers either intra-or extra-cellularly. The latter mechanism generates a localized pool of …
polymers either intra-or extra-cellularly. The latter mechanism generates a localized pool of …
Changes in interactions over ecological time scales influence single-cell growth dynamics in a metabolically coupled marine microbial community
M Daniels, S van Vliet, M Ackermann - The ISME Journal, 2023 - academic.oup.com
Microbial communities thrive in almost all habitats on earth. Within these communities, cells
interact through the release and uptake of metabolites. These interactions can have …
interact through the release and uptake of metabolites. These interactions can have …
[HTML][HTML] Bacterial growth in multicellular aggregates leads to the emergence of complex life cycles
Facultative multicellular behaviors expand the metabolic capacity and physiological
resilience of bacteria. Despite their ubiquity in nature, we lack an understanding of how …
resilience of bacteria. Despite their ubiquity in nature, we lack an understanding of how …
Resource competition predicts assembly of in vitro gut bacterial communities
Members of microbial communities interact via a plethora of mechanisms, including
resource competition, cross-feeding, and pH modulation. However, the relative contributions …
resource competition, cross-feeding, and pH modulation. However, the relative contributions …
A mutant fitness assay identifies bacterial interactions in a model ocean hot spot
Bacteria that assemble in phycospheres surrounding living phytoplankton cells metabolize a
substantial proportion of ocean primary productivity. Yet the type and extent of interactions …
substantial proportion of ocean primary productivity. Yet the type and extent of interactions …
Interspecies interactions determine growth dynamics of biopolymer-degrading populations in microbial communities
G D'Souza, J Schwartzman… - Proceedings of the …, 2023 - National Acad Sciences
Microbial communities perform essential ecosystem functions such as the remineralization
of organic carbon that exists as biopolymers. The first step in mineralization is performed by …
of organic carbon that exists as biopolymers. The first step in mineralization is performed by …
Microbial invasion of a toxic medium is facilitated by a resident community but inhibited as the community co-evolves
Predicting whether microbial invaders will colonize an environment is critical for managing
natural and engineered ecosystems, and controlling infectious disease. Invaders often face …
natural and engineered ecosystems, and controlling infectious disease. Invaders often face …
A dynamic network model predicts the phenotypes of multicellular clusters from cellular properties
Cell division without cell separation produces multicellular clusters in budding yeast. Two
fundamental characteristics of these clusters are their size (the number of cells per cluster) …
fundamental characteristics of these clusters are their size (the number of cells per cluster) …