BACKGROUND: Anastomotic leakage represents a major complication after anterior
resection of the rectum. The incidence of anastomotic leakage varies considerably among …

Perineural invasion (PNI) is a possible route for metastatic spread in various cancer types,
including colorectal cancer (CRC). PNI is linked to poor prognosis, but systematic analyses …

Background Locally advanced rectal cancer is usually treated with preoperative
chemoradiation. After chemoradiation and surgery, 15–27% of the patients have no residual …

Methods: Patients completing neoadjuvant chemoradiotherapy (CRT) for stage I to III rectal
cancer between January 2006 and August 2010 were retrospectively reviewed. Median …

Purpose The European Organisation for Research and Treatment of Cancer (EORTC) trial
evaluated the addition of chemotherapy (CT) to preoperative radiation (preop RT) and the …

Purpose To update the 2000 American Society of Clinical Oncology guideline on colorectal
cancer surveillance. Recommendations Based on results from three independently reported …

Background Cancer stem cells are associated with metastatic potential, treatment
resistance, and poor patient prognosis. Distant recurrence remains the major cause of …

Background Complete pathologic response (CPR) after neoadjuvant chemoradiotherapy
(combined modality treatment, CMT) for rectal cancer seems associated with improved …

Neoadjuvant chemoradiation therapy (CRT) is the preferred treatment option for distal rectal
cancer. Complete pathological response after CRT has led to the proposal of nonoperative …

BACKGROUND: The aim of this study was to clarify the characteristics of recurrence and the
effectiveness of surveillance tools after curative resection for colorectal cancer. METHODS …