The mood stabilizers lithium and valproic acid (VPA) are traditionally used to treat bipolar
disorder (BD), a severe mental illness arising from complex interactions between genes and …

Since its first marketing as an antiepileptic drug (AED) 35 years ago in France, valproate has
become established worldwide as one of the most widely used AEDs in the treatment of both …

Epilepsy is a brain disease characterized by abnormal electrical activity causing seizures or
unusual behaviour, sensations and sometimes loss of awareness. It carries neurological …

Overview. The Quality Standards Subcommittee seeks to develop scientifically sound,
clinically relevant practice parameters for the practice of neurology. Practice parameters are …

More than 75% of traumatic brain injuries (TBIs) seeking medical attention are mild, and
outcome in that group is heterogeneous. Until sensitive and valid biomarkers are identified …

Abstract The latest French Guidelines for the management in the first 24 hours of patients
with severe traumatic brain injury (TBI) were published in 1998. Due to recent changes …

Diverse brain insults, including traumatic brain injury, stroke, infections, tumors,
neurodegenerative diseases, and prolonged acute symptomatic seizures, such as complex …

Understanding molecular mechanisms mediating epileptogenesis is critical for developing
more effective therapies for epilepsy. We recently found that the mammalian target of …

Abstract Purpose of Review In this review, we summarize the recent literature regarding the
incidence and treatment of seizures arising after ischemic and hemorrhagic strokes …

This study examines rates of reporting of new or worse post-traumatic symptoms for patients
with a broad range of injury severity at 1 month and 1 year after traumatic brain injury (TBI) …