A review on anti-tumor mechanisms of coumarins

Y Wu, J Xu, Y Liu, Y Zeng, G Wu - Frontiers in oncology, 2020 - frontiersin.org
Coumarins are a class of compound with benzopyrone as their basic structure. Due to
abundant sources, easy synthesis, and various pharmacological activities, coumarins have …

Coumarin derivatives with anticancer activities: An update

XF Song, J Fan, L Liu, XF Liu, F Gao - Archiv der Pharmazie, 2020 - Wiley Online Library
Cancer can invade or spread to almost all parts of the body. The increasing morbidity and
high mortality of cancer create a great demand for the development of novel anticancer …

Thiosemicarbazone (s)-anchored water soluble mono-and bimetallic Cu (II) complexes: Enzyme-like activities, biomolecular interactions, anticancer property and real …

N Balakrishnan, J Haribabu, AK Dhanabalan… - Dalton …, 2020 - pubs.rsc.org
The reactions of CuCl2· 2H2O with chromone thiosemicarbazone ligands containing a–H or–
CH3 substituent on terminal N yielded monometallic Cu (II) complexes [Cu (HL1) Cl2](1) and …

A novel coumarin-chitosan fluorescent hydrogel for the selective identification of Fe 2+ in aqueous systems

S Xiong, L Duan, X Cheng - Polymer Chemistry, 2020 - pubs.rsc.org
Some new chitosan-based fluorescent hydrogels have been successfully prepared by
grafting coumarin derivatives onto chitosan via a Schiff base forming reaction or acid amine …

Overview on developed synthesis procedures of coumarin heterocycles

MM Zeydi, SJ Kalantarian, Z Kazeminejad - Journal of the Iranian …, 2020 - Springer
Considering highly valuable biological and pharmaceutical properties of coumarins, the
synthesis of these heterocycles has been considered for many organic and pharmaceutical …

Antiproliferative potential of Physalis peruviana-derived magnolin against pancreatic cancer: A comprehensive in vitro and in silico study

AM Sayed, SS El-Hawary, UR Abdelmohsen… - Food & Function, 2022 - pubs.rsc.org
Physalis peruviana L. is a common edible fruit in Egypt and other regional countries. In the
present study, we investigated its crude extract as a potential source of antiproliferative …

Anticancer mechanism of coumarin-based derivatives

AK Yadav, RM Shrestha, PN Yadav - European Journal of Medicinal …, 2024 - Elsevier
The structural motif of coumarins is related with various biological activities and
pharmacological properties. Both natural coumarin extracted from various plants or a new …

Gold (I)-Catalyzed Intramolecular Hydroarylation of Phenol-Derived Propiolates and Certain Related Ethers as a Route to Selectively Functionalized Coumarins and 2 …

A Cervi, Y Vo, CLL Chai, MG Banwell… - The Journal of …, 2020 - ACS Publications
Methods are reported for the efficient assembly of a series of phenol-derived propiolates,
including the parent system 56, and their Au (I)-catalyzed cyclization (intramolecular …

Solid-phase photochemical decarboxylative hydroalkylation of peptides

M Elkhalifa, MB Elbaum, DM Chenoweth… - Organic …, 2021 - ACS Publications
The compatibility of photochemistry with solid-phase peptide synthesis is demonstrated via
photochemical hydroalkylation to form C (sp3)–C (sp3) bonds between on-resin Giese …

Design, synthesis and biological activity evaluation of novel scopoletin-NO donor derivatives against MCF-7 human breast cancer in vitro and in vivo

N Yu, N Li, K Wang, Q Deng, Z Lei, J Sun… - European Journal of …, 2021 - Elsevier
In this study, eleven new 3-and 7-positions modified scopoletin derivatives (18a-k) were
designed, synthesized, and biologically evaluated against human breast cancer cell lines …