Application of glutathione depletion in cancer therapy: Enhanced ROS-based therapy, ferroptosis, and chemotherapy
B Niu, K Liao, Y Zhou, T Wen, G Quan, X Pan, C Wu - Biomaterials, 2021 - Elsevier
Glutathione (GSH) is an important member of cellular antioxidative system. In cancer cells, a
high level of GSH is indispensable to scavenge excessive reactive oxygen species (ROS) …
high level of GSH is indispensable to scavenge excessive reactive oxygen species (ROS) …
Antioxidant defence systems and oxidative stress in poultry biology: An update
PF Surai, II Kochish, VI Fisinin, MT Kidd - Antioxidants, 2019 - mdpi.com
Poultry in commercial settings are exposed to a range of stressors. A growing body of
information clearly indicates that excess ROS/RNS production and oxidative stress are …
information clearly indicates that excess ROS/RNS production and oxidative stress are …
Sex-specific neurotoxic effects of heavy metal pollutants: Epidemiological, experimental evidence and candidate mechanisms
The heavy metals lead (Pb), mercury (Hg), and cadmium (Cd) are ubiquitous environmental
pollutants and are known to exert severe adverse impacts on the nervous system even at …
pollutants and are known to exert severe adverse impacts on the nervous system even at …
Ferroptosis as a mechanism of non-ferrous metal toxicity
Ferroptosis is a recently discovered form of regulated cell death, implicated in multiple
pathologies. Given that the toxicity elicited by some metals is linked to alterations in iron …
pathologies. Given that the toxicity elicited by some metals is linked to alterations in iron …
[HTML][HTML] Selenium nanoparticles synthesized using an eco-friendly method: dye decolorization from aqueous solutions, cell viability, antioxidant, and antibacterial …
BA Al Jahdaly, NS Al-Radadi, GMG Eldin… - journal of materials …, 2021 - Elsevier
Selenium nanoparticles (SeNPs) were fabricated using a green microwave technique in the
presence of ascorbic acid. The morphological features indicated that the semi-spherical …
presence of ascorbic acid. The morphological features indicated that the semi-spherical …
The role of the thioredoxin system in brain diseases
The thioredoxin system, consisting of thioredoxin (Trx), thioredoxin reductase (TrxR), and
NADPH, plays a fundamental role in the control of antioxidant defenses, cell proliferation …
NADPH, plays a fundamental role in the control of antioxidant defenses, cell proliferation …
Cellular and molecular mechanisms mediating methylmercury neurotoxicity and neuroinflammation
JP Novo, B Martins, RS Raposo, FC Pereira… - International journal of …, 2021 - mdpi.com
Methylmercury (MeHg) toxicity is a major environmental concern. In the aquatic reservoir,
MeHg bioaccumulates along the food chain until it is consumed by riverine populations …
MeHg bioaccumulates along the food chain until it is consumed by riverine populations …
Progress in understanding ferroptosis and its targeting for therapeutic benefits in traumatic brain and spinal cord injuries
X Hu, Y Xu, H Xu, C Jin, H Zhang, H Su, Y Li… - Frontiers in cell and …, 2021 - frontiersin.org
Acute central nervous system (CNS) trauma, including spinal cord injury (SCI) and traumatic
brain injury (TBI), always leads to severe sensory, motor and autonomic nervous system …
brain injury (TBI), always leads to severe sensory, motor and autonomic nervous system …
Effect of methylmercury on fetal neurobehavioral development: an overview of the possible mechanisms of toxicity and the neuroprotective effect of phytochemicals
G Bjørklund, H Antonyak, A Polishchuk… - Archives of …, 2022 - Springer
Methylmercury (MeHg) is a global environmental pollutant with neurotoxic effects. Exposure
to MeHg via consumption of seafood and fish can severely impact fetal neurobehavioral …
to MeHg via consumption of seafood and fish can severely impact fetal neurobehavioral …
Mercury interactions with selenium and sulfur and the relevance of the Se: Hg molar ratio to fish consumption advice
M Gochfeld, J Burger - Environmental Science and Pollution Research, 2021 - Springer
Eating fish is often recommended as part of a healthful diet. However, fish, particularly large
predatory fish, can contain significant levels of the highly toxic methylmercury (MeHg) …
predatory fish, can contain significant levels of the highly toxic methylmercury (MeHg) …