There are two classes of glucose transporters involved in glucose homeostasis in the body,
the facilitated transporters or uniporters (GLUTs) and the active transporters or symporters …

Calcium channel β subunits have profound effects on how α 1 subunits perform. In this
article we summarize our present knowledge of the primary structures of β subunits as …

RNA editing, a post-transcriptional process, allows the diversification of proteomes beyond
the genomic blueprint; however it is infrequently used among animals for this purpose …

Potassium channels share a highly conserved stretch of eight amino acids, a K+ channel
signature sequence. The conserved sequence falls within the previously defined P-region of …

Abstract Changes in membrane potential affect ion channels and transporters, which then
alter intracellular chemical conditions. Other signalling pathways coupled to membrane …

To operate in the extreme cold, ion channels from psychrophiles must have evolved
structural changes to compensate for their thermal environment. A reasonable assumption …

The overall sequence similarity between the voltage-activated K+ channels and cyclic
nucleotide-gated ion channels from retinal and olfactory neurons suggests that they arose …

We examined voltage-dependent conformational changes in three specific regions of the
Shaker potassium channel with site-directed fluorescent labeling: the fourth transmembrane …

In voltage-dependent ion channels, a voltage sensor region is responsible for channel
activation and an aqueous pore is responsible for ion conduction. These two processes …

Voltage-dependent gating behavior of Shaker potassium channels without N-type
inactivation (ShB delta 6-46) expressed in Xenopus oocytes was studied. The voltage …