Implantation of neural probes in the brain elicits oxidative stress

ES Ereifej, GM Rial, JK Hermann, CS Smith… - … in bioengineering and …, 2018 - frontiersin.org
Clinical implantation of intracortical microelectrodes has been hindered, at least in part, by
the perpetual inflammatory response occurring after device implantation. The …

The roles of blood-derived macrophages and resident microglia in the neuroinflammatory response to implanted intracortical microelectrodes

M Ravikumar, S Sunil, J Black, DS Barkauskas… - Biomaterials, 2014 - Elsevier
Resident microglia and blood-borne macrophages have both been implicated to play a
dominant role in mediating the neuroinflammatory response affecting implanted intracortical …

Biological, mechanical, and technological considerations affecting the longevity of intracortical electrode recordings

JP Harris, DJ Tyler - Critical Reviews™ in Biomedical …, 2013 - dl.begellhouse.com
Intracortical electrodes are important tools, with applications ranging from fundamental
laboratory studies to potential solutions to intractable clinical applications. However, the …

Characterization of the neuroinflammatory response to thiol-ene shape memory polymer coated intracortical microelectrodes

AJ Shoffstall, M Ecker, V Danda, A Joshi-Imre, A Stiller… - Micromachines, 2018 - mdpi.com
Thiol-ene based shape memory polymers (SMPs) have been developed for use as
intracortical microelectrode substrates. The unique chemistry provides precise control over …

[图书][B] The glia-neuronal response to cortical electrodes: interactions with substrate stiffness and electrophysiology

JP Harris - 2011 - search.proquest.com
The overall goal of this work is to improve intracortical electrodes for chronic recordings from
the brain. The studies in the dissertation examine material stiffness, the tissue response, and …

[图书][B] The Role of Innate Immunity in the Response to Intracortical Microelectrodes

JK Hermann - 2018 - search.proquest.com
Intracortical microelectrodes exhibit enormous potential for researching the nervous system,
steering assistive devices and functional electrode stimulation (FES) systems for severely …

[图书][B] Investigation of Material and Therapeutic Strategies to Reduce the Inflammatory Response to Intracortical Implants

JK Nguyen - 2015 - search.proquest.com
Intracortical microelectrodes have provided researchers with a tool to understand the neural
system and restore motor control in patients with tetraplegia. However, recording instability …