Objectives: To determine whether a multidisciplinary, multimodal Patient Blood Management
(PBM) program for patients undergoing surgery is effective in reducing perioperative …

Background Severe bleeding and coagulopathy are serious clinical conditions that are
associated with high mortality. Thromboelastography (TEG) and thromboelastometry …

Importance Red blood cell transfusion is a common medical intervention with benefits and
harms. Objective To provide recommendations for use of red blood cell transfusion in adults …

Owing to the constantly evolving nature of the medical literature, the Society of Thoracic
Surgeons (STS) clinical practice guidelines periodically undergoes evaluation and updating …

Background The effect of a restrictive versus liberal red-cell transfusion strategy on clinical
outcomes in patients undergoing cardiac surgery remains unclear. Methods In this …

Importance Blood transfusion is one of the most frequently used therapies worldwide and is
associated with benefits, risks, and costs. Objective To develop a set of evidence-based …

Importance More than 100 million units of blood are collected worldwide each year, yet the
indication for red blood cell (RBC) transfusion and the optimal length of RBC storage prior to …

Background Severe traumatic injury continues to present challenges to healthcare systems
around the world, and post-traumatic bleeding remains a leading cause of potentially …

Background Severe trauma continues to represent a global public health issue and mortality
and morbidity in trauma patients remains substantial. A number of initiatives have aimed to …

Document Reviewers: Moritz WV Wyler von Ballmoos (USA), Mate Petricevic (Croatia), Arie
Pieter Kappetein (Netherlands), Miguel Sousa-Uva (Portugal), Georg Trummer (Germany) …