Expanding drug targets for 112 chronic diseases using a machine learning-assisted genetic priority score
Identifying genetic drivers of chronic diseases is necessary for drug discovery. Here, we
develop a machine learning-assisted genetic priority score, which we call ML-GPS, that …
develop a machine learning-assisted genetic priority score, which we call ML-GPS, that …
Prediction of diagnosis and diastolic filling pressure by AI-enhanced cardiac MRI: a modelling study of hospital data
DH Lehmann, B Gomes, N Vetter, O Braun… - The Lancet Digital …, 2024 - thelancet.com
Background With increasing numbers of patients and novel drugs for distinct causes of
systolic and diastolic heart failure, automated assessment of cardiac function is important …
systolic and diastolic heart failure, automated assessment of cardiac function is important …
[HTML][HTML] Exploring the Common Genetic Underpinnings of Chronic Pulmonary Disease and Esophageal Carcinoma Susceptibility
D Zhang, T Lu, J Li, L Zhu, S Li, Y Li, X Duan - Journal of Cancer, 2024 - ncbi.nlm.nih.gov
Background: Pulmonary diseases and esophageal cancer are highly prevalent conditions
with rising incidence worldwide. Prior evidence supports shared environmental and …
with rising incidence worldwide. Prior evidence supports shared environmental and …
Thoracic Aortic 3-Dimensional Geometry: Effects of Aging and Genetic Determinants
Background Aortic structure impacts cardiovascular health through multiple mechanisms.
Aortic structural degeneration occurs with aging, increasing left ventricular afterload and …
Aortic structural degeneration occurs with aging, increasing left ventricular afterload and …
[HTML][HTML] Utilizing multimodal AI to improve genetic analyses of cardiovascular traits
Electronic health records, biobanks, and wearable biosensors contain multiple high-
dimensional clinical data (HDCD) modalities (eg, ECG, Photoplethysmography (PPG), and …
dimensional clinical data (HDCD) modalities (eg, ECG, Photoplethysmography (PPG), and …
Assessment of valvular function in over 47,000 people using deep learning-based flow measurements
Valvular heart disease is associated with a high global burden of disease. Even mild aortic
stenosis confers increased morbidity and mortality, prompting interest in understanding …
stenosis confers increased morbidity and mortality, prompting interest in understanding …
[HTML][HTML] Newsletter da SPEDM Tema de Capa-Do Deep Blue ao DeepFlow: O Impacto Crescente da Inteligência Artificial na Medicina-Bruna Gomes
B Gomes - spedm.pt
Aplicações de inteligência artificial (IA) não são novas. Um exemplo pioneiro e emblemático
foi o programa de xadrez" Deep Blue" da IBM (Hsu 2002), que em 1997 conseguiu derrotar …
foi o programa de xadrez" Deep Blue" da IBM (Hsu 2002), que em 1997 conseguiu derrotar …