The Candida albicans reference strain SC5314 contains a rare, dominant allele of the transcription factor Rob1 that modulates filamentation, biofilm formation, and …
VE Glazier, J Kramara, T Ollinger, NV Solis… - MBio, 2023 - Am Soc Microbiol
Candida albicans is a diploid human fungal pathogen that displays significant genomic and
phenotypic heterogeneity over a range of virulence traits and in the context of a variety of …
phenotypic heterogeneity over a range of virulence traits and in the context of a variety of …
[HTML][HTML] Host immune response against fungal biofilms
Highlights•Fungal biofilms are an attached community of cells enclosed in extracellular
polymeric matrix (ECM).•ECM hide fungal ligands and block phagocytosis, NETosis, and …
polymeric matrix (ECM).•ECM hide fungal ligands and block phagocytosis, NETosis, and …
[HTML][HTML] The protective role of the Candida biofilm matrix in drug and immune protection
S Roy, NAR Gow - The Cell Surface, 2023 - Elsevier
Candida albicans, Candida auris and Candida tropicalis are three fungal pathogens that
WHO recently reported as requiring urgent attention and additional resources for research …
WHO recently reported as requiring urgent attention and additional resources for research …
Cyclic strain of Poly (methyl methacrylate) surfaces triggered the pathogenicity of Candida albicans
Candida albicans is an opportunistic yeast and the primary etiological factor in oral
candidiasis and denture stomatitis. The pathogenesis of C. albicans could be triggered by …
candidiasis and denture stomatitis. The pathogenesis of C. albicans could be triggered by …
High-Throughput Screening of the Repurposing Hub Library to Identify Drugs with Novel Inhibitory Activity against Candida albicans and Candida auris Biofilms
OH Ajetunmobi, G Wall, B Vidal Bonifacio… - Journal of Fungi, 2023 - mdpi.com
Candidiasis is one of the most frequent nosocomial infections affecting an increasing
number of at-risk patients. Candida albicans remains the most frequent causative agent of …
number of at-risk patients. Candida albicans remains the most frequent causative agent of …
Systematic analysis of the Candida albicans kinome reveals environmentally contingent protein kinase-mediated regulation of filamentation and biofilm formation in …
J Kramara, MJ Kim, TL Ollinger, LC Ristow… - mBio, 2024 - journals.asm.org
Protein kinases are critical regulatory proteins in both prokaryotes and eukaryotes.
Accordingly, protein kinases represent a common drug target for a wide range of human …
Accordingly, protein kinases represent a common drug target for a wide range of human …
Candida albicans Biofilm-Derived Extracellular Vesicles Are Involved in the Tolerance to Caspofungin, Biofilm Detachment, and Fungal Proteolytic Activity
J Karkowska-Kuleta, K Kulig, G Bras, K Stelmaszczyk… - Journal of Fungi, 2023 - mdpi.com
It has been repeatedly reported that the cells of organisms in all kingdoms of life produce
nanometer-sized lipid membrane-enveloped extracellular vesicles (EVs), transporting and …
nanometer-sized lipid membrane-enveloped extracellular vesicles (EVs), transporting and …
[HTML][HTML] The Candida albicans reference strain SC5314 contains a rare, dominant allele of the transcription factor Rob1 that modulates biofilm formation and oral …
VE Glazier, J Kramara, T Ollinger, NV Solis… - bioRxiv, 2023 - ncbi.nlm.nih.gov
Candida albicans is a diploid human fungal pathogen that displays significant genomic and
phenotypic heterogeneity over a range of virulence traits and in the context of a variety of …
phenotypic heterogeneity over a range of virulence traits and in the context of a variety of …
Biofilm formation by the fungus Phaeomoniella chlamydospora: a causal agent of esca disease of grapevine
Z Karácsony, N Molnár, D Szabó, N Bakos-Barczi… - Mycological …, 2024 - Springer
The present study suggests that the Esca pathogenic fungus Phaeomoniella chlamydospora
can form biofilm in vitro and possibly in the grapevine host tissues. This phenomenon was …
can form biofilm in vitro and possibly in the grapevine host tissues. This phenomenon was …
SCRAPPY-a single cell rapid assay of proteome perturbation in yeast uncovers a joint role of aromatic amino acids and oxidative stress in the toxicity of lipophilic …
Assaying cellular responses to antimicrobial molecules is a path to understanding modes of
action of potential drugs. This is often achieved via transcriptomics and proteomics, but …
action of potential drugs. This is often achieved via transcriptomics and proteomics, but …