Surface-functionalized PEGylated nanoparticles deliver messenger RNA to pulmonary immune cells
Nanoparticles designed as messenger RNA (mRNA) carriers to deliver gene medicine have
shown great potential to change the way lung disease states are managed. Controlling their …
shown great potential to change the way lung disease states are managed. Controlling their …
mRNA nanodelivery systems: targeting strategies and administration routes
M Yuan, Z Han, Y Liang, Y Sun, B He… - Biomaterials …, 2023 - spj.science.org
With the great success of coronavirus disease (COVID-19) messenger ribonucleic acid
(mRNA) vaccines, mRNA therapeutics have gained significant momentum for the prevention …
(mRNA) vaccines, mRNA therapeutics have gained significant momentum for the prevention …
Flash nanocomplexation (FNC): A new microvolume mixing method for nanomedicine formulation
K Li, Y Wang, Y Xu, G Shi, S Wei, X Zhang… - Chinese Chemical …, 2024 - Elsevier
The application of nanotechnologies in formulation has significantly promoted the
development of modern medical and pharmacological science, especially for nanoparticle …
development of modern medical and pharmacological science, especially for nanoparticle …
PEG400-mediated nanocarriers improve the delivery and therapeutic efficiency of mRNA tumor vaccines
W Xiao, F Wang, Y Gu, X He, N Fan, Q Zheng… - Chinese Chemical …, 2024 - Elsevier
Dendritic cell (DC)-targeted delivery of mRNA is a prominent method to boost the efficacy of
mRNA tumor vaccines. The targeting ligands are often modified on nanocarriers by …
mRNA tumor vaccines. The targeting ligands are often modified on nanocarriers by …
Hepatocyte Growth Factor Delivered by Nanocomposites for Gene Therapy of Bleomycin-Induced Pulmonary Fibrosis in Rats
Q Guo, Y Lu, X Cheng, F Xiao, Q Zhang… - Current Drug …, 2023 - ingentaconnect.com
Background: Pulmonary fibrosis (PF) is a chronic and progressive interstitial lung disease.
There is no effective treatment for PF. Hepatocyte growth factor (HGF) has anti-inflammatory …
There is no effective treatment for PF. Hepatocyte growth factor (HGF) has anti-inflammatory …
Zn (ii)-Dipicolylamine analogues with amphiphilic side chains endow low molecular weight PEI with high transfection performance
To investigate the effect of amphiphilic balance of Zn (II)-dipicolylamine analogues on the
transfection process, we fabricated a series of Zn (II)-dipicolylamine functional modules …
transfection process, we fabricated a series of Zn (II)-dipicolylamine functional modules …