Mechanisms of 3D cell migration

KM Yamada, M Sixt - Nature Reviews molecular cell biology, 2019 - nature.com
Cell migration is essential for physiological processes as diverse as development, immune
defence and wound healing. It is also a hallmark of cancer malignancy. Thousands of …

Unravelling cell migration: defining movement from the cell surface

F Merino-Casallo, MJ Gomez-Benito… - Cell adhesion & …, 2022 - Taylor & Francis
Cell motility is essential for life and development. Unfortunately, cell migration is also linked
to several pathological processes, such as cancer metastasis. Cells' ability to migrate relies …

Generation of stress fibers through myosin-driven reorganization of the actin cortex

JI Lehtimäki, EK Rajakylä, S Tojkander, P Lappalainen - Elife, 2021 - elifesciences.org
Contractile actomyosin bundles, stress fibers, govern key cellular processes including
migration, adhesion, and mechanosensing. Stress fibers are thus critical for developmental …

Vascular surveillance by haptotactic blood platelets in inflammation and infection

L Nicolai, K Schiefelbein, S Lipsky, A Leunig… - Nature …, 2020 - nature.com
Breakdown of vascular barriers is a major complication of inflammatory diseases. Anucleate
platelets form blood-clots during thrombosis, but also play a crucial role in inflammation …

[HTML][HTML] Nanomechanics of the endothelial glycocalyx: from structure to function

ZC Cosgun, B Fels, K Kusche-Vihrog - The American journal of pathology, 2020 - Elsevier
The negatively charged, brush-like glycocalyx covers the surface layer of endothelial cells.
This layer of membrane-bound, carbohydrate-rich molecules covers the luminal surface of …

Regulation of actin dynamics by PI (4, 5) P2 in cell migration and endocytosis

Y Senju, P Lappalainen - Current opinion in cell biology, 2019 - Elsevier
The actin cytoskeleton is indispensable for several cellular processes, including migration,
morphogenesis, polarized growth, endocytosis, and phagocytosis. The organization and …

The makings of the 'actin code': regulation of actin's biological function at the amino acid and nucleotide level

P Vedula, A Kashina - Journal of cell science, 2018 - journals.biologists.com
The actin cytoskeleton plays key roles in every eukaryotic cell and is essential for cell
adhesion, migration, mechanosensing, and contractility in muscle and non-muscle tissues …

Intrinsic mechanisms regulating neuronal migration in the postnatal brain

C Bressan, A Saghatelyan - Frontiers in Cellular Neuroscience, 2021 - frontiersin.org
Neuronal migration is a fundamental brain development process that allows cells to move
from their birthplaces to their sites of integration. Although neuronal migration largely ceases …

[HTML][HTML] Role of actin-binding proteins in the regulation of cellular mechanics

AV Vakhrusheva, AV Murashko, ES Trifonova… - European Journal of …, 2022 - Elsevier
The viscoelastic parameters of the cell can report on the cell state, cellular processes and
diseases. Cell mechanics strongly rely on the properties of the cytoskeleton, an important …

Wound healing activity of nanoclay/spring water hydrogels

F García-Villén, A Faccendini, D Miele, M Ruggeri… - Pharmaceutics, 2020 - mdpi.com
Background: hydrogels prepared with natural inorganic excipients and spring waters are
commonly used in medical hydrology. Design of these clay-based formulations continues to …