Mechanisms of 3D cell migration
Cell migration is essential for physiological processes as diverse as development, immune
defence and wound healing. It is also a hallmark of cancer malignancy. Thousands of …
defence and wound healing. It is also a hallmark of cancer malignancy. Thousands of …
Unravelling cell migration: defining movement from the cell surface
F Merino-Casallo, MJ Gomez-Benito… - Cell adhesion & …, 2022 - Taylor & Francis
Cell motility is essential for life and development. Unfortunately, cell migration is also linked
to several pathological processes, such as cancer metastasis. Cells' ability to migrate relies …
to several pathological processes, such as cancer metastasis. Cells' ability to migrate relies …
Generation of stress fibers through myosin-driven reorganization of the actin cortex
JI Lehtimäki, EK Rajakylä, S Tojkander, P Lappalainen - Elife, 2021 - elifesciences.org
Contractile actomyosin bundles, stress fibers, govern key cellular processes including
migration, adhesion, and mechanosensing. Stress fibers are thus critical for developmental …
migration, adhesion, and mechanosensing. Stress fibers are thus critical for developmental …
Vascular surveillance by haptotactic blood platelets in inflammation and infection
Breakdown of vascular barriers is a major complication of inflammatory diseases. Anucleate
platelets form blood-clots during thrombosis, but also play a crucial role in inflammation …
platelets form blood-clots during thrombosis, but also play a crucial role in inflammation …
[HTML][HTML] Nanomechanics of the endothelial glycocalyx: from structure to function
ZC Cosgun, B Fels, K Kusche-Vihrog - The American journal of pathology, 2020 - Elsevier
The negatively charged, brush-like glycocalyx covers the surface layer of endothelial cells.
This layer of membrane-bound, carbohydrate-rich molecules covers the luminal surface of …
This layer of membrane-bound, carbohydrate-rich molecules covers the luminal surface of …
Regulation of actin dynamics by PI (4, 5) P2 in cell migration and endocytosis
Y Senju, P Lappalainen - Current opinion in cell biology, 2019 - Elsevier
The actin cytoskeleton is indispensable for several cellular processes, including migration,
morphogenesis, polarized growth, endocytosis, and phagocytosis. The organization and …
morphogenesis, polarized growth, endocytosis, and phagocytosis. The organization and …
The makings of the 'actin code': regulation of actin's biological function at the amino acid and nucleotide level
The actin cytoskeleton plays key roles in every eukaryotic cell and is essential for cell
adhesion, migration, mechanosensing, and contractility in muscle and non-muscle tissues …
adhesion, migration, mechanosensing, and contractility in muscle and non-muscle tissues …
Intrinsic mechanisms regulating neuronal migration in the postnatal brain
C Bressan, A Saghatelyan - Frontiers in Cellular Neuroscience, 2021 - frontiersin.org
Neuronal migration is a fundamental brain development process that allows cells to move
from their birthplaces to their sites of integration. Although neuronal migration largely ceases …
from their birthplaces to their sites of integration. Although neuronal migration largely ceases …
[HTML][HTML] Role of actin-binding proteins in the regulation of cellular mechanics
AV Vakhrusheva, AV Murashko, ES Trifonova… - European Journal of …, 2022 - Elsevier
The viscoelastic parameters of the cell can report on the cell state, cellular processes and
diseases. Cell mechanics strongly rely on the properties of the cytoskeleton, an important …
diseases. Cell mechanics strongly rely on the properties of the cytoskeleton, an important …
Wound healing activity of nanoclay/spring water hydrogels
F García-Villén, A Faccendini, D Miele, M Ruggeri… - Pharmaceutics, 2020 - mdpi.com
Background: hydrogels prepared with natural inorganic excipients and spring waters are
commonly used in medical hydrology. Design of these clay-based formulations continues to …
commonly used in medical hydrology. Design of these clay-based formulations continues to …