Phlorotannins from brown algae: A review on their antioxidant mechanisms and applications in oxidative stress-mediated diseases

SJ Phang, HX Teh, ML Looi, B Arumugam… - Journal of Applied …, 2023 - Springer
Phlorotannins are polyphenolic compounds that are exclusively derived from marine brown
algae. The molecular structure of phlorotannins with numerous phenol rings endows them …

[HTML][HTML] The effect of flaxseed supplementation on glycemic control in adults: an updated systematic review and meta-analysis of randomized controlled trials

Z Kavyani, P Pourfarziani, AMJ Kakhki… - Journal of Functional …, 2023 - Elsevier
Recent randomized controlled trials (RCTs) have shown that flaxseed supplementation
beneficially improves glycemic control; however, there is no consensus on this issue. In this …

[HTML][HTML] Bioassay-guided identification of potential Alzheimer's disease therapeutic agents from Kaempferol-Enriched fraction of Aframomum melegueta seeds using …

IF Chukwuma, TPC Ezeorba, FN Nworah… - Arabian Journal of …, 2023 - Elsevier
Alzheimer's disease (AD) has become a major public health concern and the fifth major
cause of death among the aging population globally. In this study, the total phenols and …

[HTML][HTML] Nephroprotective effects of Piper nigrum extracts against monosodium glutamate-induced renal toxicity in rats

CO Onyesife, IF Chukwuma, IU Okagu, JC Ndefo… - Scientific African, 2023 - Elsevier
Background The toxicological effects of monosodium glutamate (MSG), widely used as a
food additive, are a major public health challenge. This research aimed to investigate the …

Virtual screening strategy for anti-DPP-IV natural flavonoid derivatives based on machine learning

G Lu, F Pan, X Li, Z Zhu, L Zhao, Y Wu… - Journal of …, 2023 - Taylor & Francis
Flavonoids, especially their inhibitory effect on DPP-IV activity, have been widely recognized
for their antidiabetic effects. However, the variety of natural flavonoid derivatives is very rich …

[HTML][HTML] Phytocompounds, antioxidant potential, and inhibitory actions of ethanolic leaf fraction of Sida linifolia Linn. (Malvaceae) on enzymes linked to inflammation …

EC Ezeako, FN Nworah, DO Osuji - Future Journal of Pharmaceutical …, 2023 - Springer
Background Sida linifolia L. is a weed ubiquitously found in Africa with several folkloric
applications. Traditional healers in the Southeastern part of Nigeria employ the alcoholic …

[HTML][HTML] An in silico study of bioactive compounds of Annona muricata in the design of ani-prostate cancer agent: MM/GBSA, pharmacophore modeling and ADMET …

VO Apeh, AE Adegboyega, IF Chukwuma… - Informatics in Medicine …, 2023 - Elsevier
One of the most frequent diseases that affect and kill men globally is prostate cancer.
Treatment for prostate cancer has become unpleasant and upsetting for individuals due to …

[HTML][HTML] Changes in nutritional, health benefits, and pharmaceutical potential of raw and roasted tropical almond (Terminalia catappa Linn.) nuts from Nigeria

IF Chukwuma, EC Ossai, FN Nworah, VO Apeh… - Plos one, 2024 - journals.plos.org
Tropical almond (Terminalia catappa Linn.) is highly distributed within the tropics, but
appears rather underutilized in developing countries like Nigeria. Specifically, relevant …

[HTML][HTML] Effects of Silybum marianum L. Seed Extracts on Multi Drug Resistant (MDR) Bacteria

S El-Sapagh, NG Allam, MNED El-Sayed… - Molecules, 2023 - mdpi.com
Wound infections became a great challenge, especially after the emergence of bacterial
resistance to commonly used antibiotics. Medicinal plants can be the source of alternative …

[HTML][HTML] Could eggshell membrane be an adjuvant for recombinant Hepatitis B vaccine?: A preliminary investigation

PE Joshua, CC Ilo, UG Ukachukwu… - Future Journal of …, 2023 - Springer
Background Despite the invasiveness of the Hepatitis B infection, its vaccines are only
formulated with FDA-approved alum-based adjuvants, which poorly elicit a lasting immune …