DNA functional materials assembled from branched DNA: design, synthesis, and applications

Y Dong, C Yao, Y Zhu, L Yang, D Luo… - Chemical Reviews, 2020 - ACS Publications
DNA is traditionally known as a central genetic biomolecule in living systems. From an
alternative perspective, DNA is a versatile molecular building-block for the construction of …

Nanogels: Synthesis, properties, and recent biomedical applications

QY Duan, YX Zhu, HR Jia, SH Wang, FG Wu - Progress in Materials …, 2023 - Elsevier
Nanogels, also termed hydrogel nanoparticles, have the properties and functions of both
nanomaterials and hydrogels. Till date, a considerable number of nanogels have been …

pH-Sensitive nanogels for drug delivery in cancer therapy

Z Li, J Huang, J Wu - Biomaterials Science, 2021 - pubs.rsc.org
As a commonly used treatment method for cancer, chemotherapy is greatly limited by the
side effects of chemotherapy drugs and the multiple drug resistance that develops …

Smart and functionalized development of nucleic acid‐based hydrogels: Assembly strategies, recent advances, and challenges

Y Zhang, L Zhu, J Tian, L Zhu, X Ma, X He… - Advanced …, 2021 - Wiley Online Library
Nucleic acid‐based hydrogels that integrate intrinsic biological properties of nucleic acids
and mechanical behavior of their advanced assemblies are appealing bioanalysis and …

Reconfigurable A-motif, i-motif and triplex nucleic acids for smart pH-responsive DNA hydrogels

Y Hu, JY Ying - Materials Today, 2023 - Elsevier
Integrating dynamic reconfigurable DNA crosslinking units, smart DNA hydrogels have
demonstrated sol–gel transition, shape memory, self-healing, sensing, cargo encapsulation …

Destruction of tumor vasculature by vascular disrupting agents in overcoming the limitation of EPR effect

Z Liu, Y Zhang, N Shen, J Sun, Z Tang… - Advanced Drug Delivery …, 2022 - Elsevier
Nanomedicine greatly improves the efficiency in the delivery of antitumor drugs into the
tumor, but insufficient tumoral penetration impairs the therapeutic efficacy of most …

DNA‐based nanoarchitectures as eminent vehicles for smart drug delivery systems

M Komiyama, N Shigi, K Ariga - Advanced Functional Materials, 2022 - Wiley Online Library
In order to cure diseases efficiently with minimal side effects in sophisticated medicine,
eminent drugs must be selectively delivered to diseased parts and allow to work only there …

pH-responsive DNA hydrogels with ratiometric fluorescence for accurate detection of miRNA-21

S Yao, L Xiang, L Wang, H Gong, F Chen, C Cai - Analytica Chimica Acta, 2022 - Elsevier
DNA hydrogels are powerful candidates for stable and sensitive detection of disease-related
nucleic acids. However, the ability to accurately detect is the cornerstone of disease …

Construction of nanocarriers based on nucleic acids and their applications in nanobiology delivery systems

Y Guo, X Cao, X Zheng, SJ Abbas, J Li… - National Science …, 2022 - academic.oup.com
In recent years, nanocarriers based on nucleic acids have emerged as powerful and novel
nanocarriers that are able to meet the demand for cancer-cell-specific targeting. Functional …

Hydrogel-mediated drug delivery for treating stroke

W Yu, E Gong, B Liu, L Zhou, C Che, S Hu… - Chinese Chemical …, 2023 - Elsevier
Stroke is a common disease and is the major cause of death and disability. It occurs and
generates devastating neurological deficits when cerebral blood vessel is blocked (ischemic …