A guide to human zinc absorption: general overview and recent advances of in vitro intestinal models

M Maares, H Haase - Nutrients, 2020 - mdpi.com
Zinc absorption in the small intestine is one of the main mechanisms regulating the systemic
homeostasis of this essential trace element. This review summarizes the key aspects of …

[HTML][HTML] Zinc dysregulation in cancers and its potential as a therapeutic target

J Wang, H Zhao, Z Xu, X Cheng - Cancer biology & medicine, 2020 - ncbi.nlm.nih.gov
Zinc is an essential element and serves as a structural or catalytic component in many
proteins. Two families of transporters are involved in maintaining cellular zinc homeostasis …

Mitochondria at the interface between neurodegeneration and neuroinflammation

V Bader, KF Winklhofer - Seminars in cell & developmental biology, 2020 - Elsevier
Mitochondria are essential organelles for the maintenance of neuronal integrity, based on
their manifold functions in regulating cellular metabolism and coordinating cell death and …

Lessons in organic fluorescent probe discovery

SB Wagh, VA Maslivetc, JJ La Clair… - ChemBioChem, 2021 - Wiley Online Library
Fluorescent probes have gained profound use in biotechnology, drug discovery, medical
diagnostics, molecular and cell biology. The development of methods for the translation of …

The cell biology of zinc

S Clemens - Journal of Experimental Botany, 2022 - academic.oup.com
Nearly 10% of all plant proteins belong to the zinc (Zn) proteome. They require Zn either for
catalysis or as a structural element. Most of the protein-bound Zn in eukaryotic cells is found …

Tools and techniques for illuminating the cell biology of zinc

EPS Pratt, LJ Damon, KJ Anson, AE Palmer - Biochimica et Biophysica Acta …, 2021 - Elsevier
Abstract Zinc (Zn 2+) is an essential micronutrient that is required for a wide variety of
cellular processes. Tools and methods have been instrumental in revealing the myriad roles …

The role of the metabolism of zinc and manganese ions in human cancerogenesis

JM Rozenberg, M Kamynina, M Sorokin… - Biomedicines, 2022 - mdpi.com
Metal ion homeostasis is fundamental for life. Specifically, transition metals iron, manganese
and zinc play a pivotal role in mitochondrial metabolism and energy generation, anti …

[HTML][HTML] Structural zinc binding sites shaped for greater works: Structure-function relations in classical zinc finger, hook and clasp domains

M Padjasek, A Kocyła, K Kluska, O Kerber… - Journal of Inorganic …, 2020 - Elsevier
Metal ions are essential elements present in biological systems able to facilitate many
cellular processes including proliferation, signaling, DNA synthesis and repair. Zinc ion (Zn …

Fluorescein derived Schiff base as fluorimetric zinc (II) sensor via 'turn on'response and its application in live cell imaging

B Das, A Jana, AD Mahapatra, D Chattopadhyay… - … Acta Part A: Molecular …, 2019 - Elsevier
A novel Schiff base L composed of fluorescein hydrazine and a phenol functionalized moiety
has been designed and prepared via cost-effective condensation reaction. The L is utilized …

Zinc homeostasis in diabetes mellitus and vascular complications

S MacKenzie, A Bergdahl - Biomedicines, 2022 - mdpi.com
Oxidative stress represents an impaired metabolic system that promotes damage to cells
and tissues. This is the predominant factor that leads to the development and progression of …