The biologically relevant coordination chemistry of iron and nitric oxide: electronic structure and reactivity
Nitric oxide (NO) is an important signaling molecule that is involved in a wide range of
physiological and pathological events in biology. Metal coordination chemistry, especially …
physiological and pathological events in biology. Metal coordination chemistry, especially …
How biology handles nitrite
Nitrite is one of the players in the broad nitrogen biogeochemical cycle. This nitrogen oxo-
anion is involved in key pathways crucial to life on Earth and to the planetary “recycling” of …
anion is involved in key pathways crucial to life on Earth and to the planetary “recycling” of …
Electronic structure of heme-nitrosyls and its significance for nitric oxide reactivity, sensing, transport, and toxicity in biological systems
LE Goodrich, F Paulat, VKK Praneeth… - Inorganic …, 2010 - ACS Publications
This review summarizes recent developments in the investigation of the electronic
structures, spectroscopic properties, and reactivities of ferrous and ferric heme-nitrosyls and …
structures, spectroscopic properties, and reactivities of ferrous and ferric heme-nitrosyls and …
New features in the redox coordination chemistry of metal nitrosyls {M–NO+; M–NO; M–NO−(HNO)}
We describe new developments in the coordination chemistry of bound nitrosyl, considering
its three formal redox states: NO+, NO and NO−/HNO. We emphasize on the correlation …
its three formal redox states: NO+, NO and NO−/HNO. We emphasize on the correlation …
Short-lived intermediate in N2O generation by P450 NO reductase captured by time-resolved IR spectroscopy and XFEL crystallography
T Nomura, T Kimura, Y Kanematsu… - Proceedings of the …, 2021 - National Acad Sciences
Nitric oxide (NO) reductase from the fungus Fusarium oxysporum is a P450-type enzyme
(P450nor) that catalyzes the reduction of NO to nitrous oxide (N2O) in the global nitrogen …
(P450nor) that catalyzes the reduction of NO to nitrous oxide (N2O) in the global nitrogen …
Azanone (HNO): generation, stabilization and detection
HNO (nitroxyl, azanone), joined the 'biologically relevant reactive nitrogen species' family in
the 2000s. Azanone is impossible to store due to its high reactivity and inherent low stability …
the 2000s. Azanone is impossible to store due to its high reactivity and inherent low stability …
Stabilization of a Heme-HNO Model Complex Using a Bulky Bis-Picket Fence Porphyrin and Reactivity Studies with NO
EC Manickas, AB LaLonde, MY Hu… - Journal of the …, 2023 - ACS Publications
Nitroxyl, HNO/NO–, the one-electron reduced form of NO, is suggested to take part in distinct
signaling pathways in mammals and is also a key intermediate in various heme-catalyzed …
signaling pathways in mammals and is also a key intermediate in various heme-catalyzed …
Six-Electron Reduction of Nitrite to Ammonia by Cytochrome c Nitrite Reductase: Insights from Density Functional Theory Studies
In this Forum Article, an extensive discussion of the mechanism of six-electron, seven-proton
nitrite reduction by the cytochrome c nitrite reductase enzyme is presented. On the basis of …
nitrite reduction by the cytochrome c nitrite reductase enzyme is presented. On the basis of …
The effects of nitroxyl (HNO) on soluble guanylate cyclase activity: interactions at ferrous heme and cysteine thiols
TW Miller, MM Cherney, AJ Lee, NE Francoleon… - Journal of Biological …, 2009 - ASBMB
It has been previously proposed that nitric oxide (NO) is the only biologically relevant
nitrogen oxide capable of activating the enzyme soluble guanylate cyclase (sGC). However …
nitrogen oxide capable of activating the enzyme soluble guanylate cyclase (sGC). However …
Nitroxyl (azanone) trapping by metalloporphyrins
The present review starts describing nitroxyl (azanone, 1HNO) biological relevance, in
relation with NO physiology, from a chemical reactivity perspective. After a description of …
relation with NO physiology, from a chemical reactivity perspective. After a description of …