Deficits in neuronal function are a hallmark of spinal cord injury (SCI) and therapeutic efforts
are often focused on central nervous system (CNS) axon regeneration. However, secondary …

Spinal cord injury can lead to severe motor, sensory and autonomic dysfunction. Currently,
there is no effective treatment for the injured spinal cord. The transplantation of Schwann …

Neuropsychological deficits, including impairments in learning and memory, occur after
spinal cord injury (SCI). In experimental SCI models, we and others have reported that such …

Glial cell types were classified less than 100 years ago by del Rio-Hortega. For instance, he
correctly surmised that microglia in pathologic central nervous system (CNS) were …

Spinal cord injury (SCI) is a life-shattering neurological condition that affects between
250,000 and 500,000 individuals each year with an estimated two to three million people …

MicroRNAs (miRNAs) are small noncoding RNAs that broadly affect cellular and
physiological function in all multicellular organisms. Here, the role of miRNAs in …

Spinal cord injury (SCI) is a severe neurological disease; however, few drugs have been
proved to treat SCI effectively. Neuroinflammation is the major pathogenesis of SCI …

Parkinson's Disease (PD) is a chronic and progressive neurodegenerative disorder of
unknown etiology. Autopsy findings, genetics, retrospective studies, and molecular imaging …

Spinal cord injury (SCI) has a complex pathophysiology. Following the initial physical
trauma to the spinal cord, which may cause vascular disruption, hemorrhage, mechanical …

Classically activated pro-inflammatory (M1) and alternatively activated anti-inflammatory
(M2) macrophages populate the local microenvironment after spinal cord injury (SCI). The …