Clinical biology of the pituitary adenoma

S Melmed, UB Kaiser, MB Lopes, J Bertherat… - Endocrine …, 2022 - academic.oup.com
All endocrine glands are susceptible to neoplastic growth, yet the health consequences of
these neoplasms differ between endocrine tissues. Pituitary neoplasms are highly prevalent …

Multidisciplinary management of acromegaly: a consensus

A Giustina, G Barkhoudarian, A Beckers… - Reviews in Endocrine …, 2020 - Springer
Abstract The 13th Acromegaly Consensus Conference was held in November 2019 in Fort
Lauderdale, Florida, and comprised acromegaly experts including endocrinologists and …

Acromegaly: pathogenesis, diagnosis, and management

M Fleseriu, F Langlois, DST Lim… - The Lancet Diabetes & …, 2022 - thelancet.com
Growth hormone-secreting pituitary adenomas that cause acromegaly arise as monoclonal
expansions of differentiated somatotroph cells and are usually sporadic. They are almost …

Pituitary-tumor endocrinopathies

S Melmed - New England Journal of Medicine, 2020 - Mass Medical Soc
Pituitary-Tumor Endocrinopathies Pituitary adenomas account for about 15% of intracranial
tumors. Clinical manifestations of disease reflect the oversecretion of the involved hormone …

A consensus on the diagnosis and treatment of acromegaly comorbidities: an update

A Giustina, A Barkan, A Beckers… - The Journal of …, 2020 - academic.oup.com
Objective The aim of the Acromegaly Consensus Group was to revise and update the
consensus on diagnosis and treatment of acromegaly comorbidities last published in 2013 …

Insulin-like growth factor 1 (IGF-1) signaling in glucose metabolism in colorectal cancer

A Kasprzak - International journal of molecular sciences, 2021 - mdpi.com
Colorectal cancer (CRC) is one of the most common aggressive carcinoma types worldwide,
characterized by unfavorable curative effect and poor prognosis. Epidemiological data re …

Somatostatin analogs in clinical practice: a review

M Gomes-Porras, J Cárdenas-Salas… - International journal of …, 2020 - mdpi.com
Somatostatin analogs are an invaluable therapeutic option in the diagnosis and treatment of
somatotropinomas, thyrotropinomas, and functioning and non-functioning …

Consensus on criteria for acromegaly diagnosis and remission

A Giustina, N Biermasz, FF Casanueva, M Fleseriu… - Pituitary, 2024 - Springer
Abstract Purpose The 14th Acromegaly Consensus Conference was convened to consider
biochemical criteria for acromegaly diagnosis and evaluation of therapeutic efficacy …

COVID-19 and the pituitary

S Frara, A Allora, L Castellino, L di Filippo, P Loli… - Pituitary, 2021 - Springer
Background Despite COVID-19 being identified as severe respiratory viral infection,
progressively many relevant endocrine manifestations have been reported greatly …

Therapeutic targeting of the IGF axis

E Osher, VM Macaulay - Cells, 2019 - mdpi.com
The insulin like growth factor (IGF) axis plays a fundamental role in normal growth and
development, and when deregulated makes an important contribution to disease. Here, we …