This review provides an update of the genetic content, phylogeny and evolution of the family
Adenoviridae. An appraisal of the condition of adenovirus genomics highlights the need to …

The pandemic of the 2019 novel coronavirus disease (COVID-19) has brought viruses into
the public horizon. Since viruses can pose a threat to human health in a low concentration …

Adenoviruses are used extensively as gene transfer agents, both experimentally and
clinically. However, targeting of liver cells by adenoviruses compromises their potential …

An unidentified agent was cultured in primary monkey cells at the Los Angeles County
Public Health Department from each of five stool specimens submitted from an outbreak of …

Icosahedral bacteriophages pack their double-stranded DNA genomes to near-crystalline
density and achieve one of the highest levels of DNA condensation found in nature. Despite …

ABSTRACT A major impediment to the use of adenovirus as a gene therapy vector and for
vaccine applications is the host immune response to adenovirus hexon—the major protein …

During the past few years one of the most astonishing findings in the field of virology has
been the realization that viruses that infect hosts from all three domains of life are often …

Structural studies continue to play an essential role as the focus of adenovirus research
shifts in emphasis from basic biology to adenovirus-based vector technologies. A crucial …

Human adenoviruses have been the subject of intensive investigation since their discovery
in the early 1950s: they have served as model pathogens, as probes for studying cellular …

Carbohydrates, either bound to proteins or in lipids, play essential roles as communication
molecules in many intercellular and intracellular processes. In particular, carbohydrates are …