Applications of metabolomics in forensic toxicology and forensic medicine

M Szeremeta, K Pietrowska… - International Journal of …, 2021 - mdpi.com
Forensic toxicology and forensic medicine are unique among all other medical fields
because of their essential legal impact, especially in civil and criminal cases. New high …

The eye in forensic medicine: a narrative review

JL Ang, SA Collis, B Dhillon… - The Asia-Pacific Journal of …, 2021 - journals.lww.com
The eye, with its distinctive anatomy, not only reflects a wide variety of diseases in life but
also undergoes a myriad of post-mortem changes. Consequently, the eye has long been an …

The 'ForensOMICS'approach for postmortem interval estimation from human bone by integrating metabolomics, lipidomics, and proteomics

A Bonicelli, HL Mickleburgh, A Chighine, E Locci… - Elife, 2022 - elifesciences.org
The combined use of multiple omics allows to study complex interrelated biological
processes in their entirety. We applied a combination of metabolomics, lipidomics and …

Individualised and non-contact post-mortem interval determination of human bodies using visible and thermal 3D imaging

LS Wilk, GJ Edelman, M Roos, M Clerkx… - Nature …, 2021 - nature.com
Determining the time since death, ie, post-mortem interval (PMI), often plays a key role in
forensic investigations. The current standard PMI-estimation method empirically correlates …

Post-mortem changes in metabolomic profiles of human serum, aqueous humor and vitreous humor

EA Zelentsova, LV Yanshole, AD Melnikov… - Metabolomics, 2020 - Springer
Introduction Application of metabolomic methods to forensic studies may expand the limits of
the post-mortem interval (PMI) estimation, and improve the accuracy of the estimation. To …

Forensic NMR metabolomics: one more arrow in the quiver

E Locci, G Bazzano, A Chighine, F Locco, E Ferraro… - Metabolomics, 2020 - Springer
Introduction NMR metabolomics is increasingly used in forensics, due to the possibility of
investigating both endogenous metabolic profiles and exogenous molecules that may help …

Multi-omics integration strategy in the post-mortem interval of forensic science

J Li, Y Wu, M Liu, N Li, L Dang, G An, X Lu, L Wang… - Talanta, 2024 - Elsevier
Estimates of post-mortem interval (PMI), which often serve as pivotal evidence in forensic
contexts, are fundamentally based on assessments of variability among diverse molecular …

Comparative use of aqueous humour 1H NMR metabolomics and potassium concentration for PMI estimation in an animal model

E Locci, M Stocchero, R Gottardo, F De-Giorgio… - International Journal of …, 2021 - Springer
Estimation of the post-mortem interval (PMI) remains a matter of concern in the forensic
scenario. Traditional and novel approaches are not yet able to fully address this issue, which …

A novel method for determining postmortem interval based on the metabolomics of multiple organs combined with ensemble learning techniques

X Lu, J Li, X Wei, N Li, L Dang, G An, Q Du… - International Journal of …, 2023 - Springer
Determining postmortem interval (PMI) is one of the most challenging and essential
endeavors in forensic science. Developments in PMI estimation can take advantage of …

Untargeted metabolomics approaches to improve casework in clinical and forensic toxicology—“Where are we standing and where are we heading?”

AE Steuer, L Brockbals… - … Reviews: Forensic Science, 2022 - Wiley Online Library
Clinical toxicology (CT) and forensic toxicology (FT) represent two disciplines of toxicology
dedicated to the qualitative and quantitative analysis and respective interpretation of …