Peptide–and protein–nanoparticle conjugates have emerged as powerful tools for
biomedical applications, enabling the treatment, diagnosis, and prevention of disease. In …

Due to the ability of the blood–brain barrier (BBB) to prevent the entry of drugs into the brain,
it is a challenge to treat central nervous system disorders pharmacologically. The …

Inspired by considerable application potential in various diseases, nitric oxide (NO) has
gained increasing attention. Nevertheless, current NO release scaffolds suffer from some …

Various obstacles impede the chemotherapy efficiency of glioma in clinic, such as blood
brain barrier (BBB) and blood brain tumor barrier (BBTB). Ligand-mediated polymeric …

Receptor‐mediated drug delivery presents an opportunity to enhance therapeutic efficiency
by accumulating drug within the tissue of interest and reducing undesired, off‐target effects …

Chemotherapy outcomes for the treatment of glioma remain unsatisfied due to the inefficient
drug transport across BBB/BBTB and poor drug accumulation in the tumor site. Nanocarriers …

The treatment of glioma is a great challenge because of the existence of the blood-brain
barrier (BBB). In order to reduce toxicity to the normal brain tissue and achieve efficient …

Nitric oxide (NO) molecular messenger can reverse the multidrug resistance (MDR) effect of
cancer cells through reducing P-glycoprotein (P-gp) expression, beneficial for creating a …

To improve glioma targeting delivery efficiency and to monitor drug delivery and treatment
outcome, a novel tumor microenvironment sensitive size-shrinkable theranostic system was …

The treatment of central nervous system (CNS) malignancies, including brain cancers, is
limited by a number of obstructions, including the blood-brain barrier (BBB), the …