The mechanosensory neurons of touch and their mechanisms of activation

A Handler, DD Ginty - Nature Reviews Neuroscience, 2021 - nature.com
Our sense of touch emerges from an array of mechanosensory structures residing within the
fabric of our skin. These tactile end organ structures convert innocuous forces acting on the …

[HTML][HTML] Schwann cell functions in peripheral nerve development and repair

M Bosch-Queralt, R Fledrich, RM Stassart - Neurobiology of disease, 2023 - Elsevier
The glial cell of the peripheral nervous system (PNS), the Schwann cell (SC), counts among
the most multifaceted cells of the body. During development, SCs secure neuronal survival …

Perception‐to‐cognition tactile sensing based on artificial‐intelligence‐motivated human full‐skin bionic electronic skin

H Niu, H Li, S Gao, Y Li, X Wei, Y Chen… - Advanced …, 2022 - Wiley Online Library
Traditional electronic skin (e‐skin), due to the lack of human‐brain‐like thinking and judging
capability, is powerless to accelerate the pace to the intelligent era. Herein, artificial …

[HTML][HTML] Three-dimensional reconstructions of mechanosensory end organs suggest a unifying mechanism underlying dynamic, light touch

A Handler, Q Zhang, S Pang, TM Nguyen, M Iskols… - Neuron, 2023 - cell.com
Across mammalian skin, structurally complex and diverse mechanosensory end organs
respond to mechanical stimuli and enable our perception of dynamic, light touch. How forces …

Schwann Cells as Orchestrators of Nerve Repair: Implications for Tissue Regeneration and Pathologies

RM Stassart, JA Gomez-Sanchez… - Cold Spring Harbor …, 2024 - cshperspectives.cshlp.org
Peripheral nerves exist in a stable state in adulthood providing a rapid bidirectional
signaling system to control tissue structure and function. However, following injury …

Cocklebur-inspired “branch-seed-spininess” 3D hierarchical structure bionic electronic skin for intelligent perception

H Niu, H Li, Y Li, W Yue, S Gao, X Wei, G Shen - Nano Energy, 2023 - Elsevier
Traditional electronic skin (e-skin) with single micro-nano structures has a limited capacity to
optimize the comprehensive sensing properties, which greatly hinders the intellectualization …

[HTML][HTML] A mouse DRG genetic toolkit reveals morphological and physiological diversity of somatosensory neuron subtypes

L Qi, M Iskols, D Shi, P Reddy, C Walker, K Lezgiyeva… - Cell, 2024 - cell.com
Dorsal root ganglia (DRG) somatosensory neurons detect mechanical, thermal, and
chemical stimuli acting on the body. Achieving a holistic view of how different DRG neuron …

Micropyramid array bimodal electronic skin for intelligent material and surface shape perception based on capacitive sensing

H Niu, X Wei, H Li, F Yin, W Wang, RS Seong… - Advanced …, 2024 - Wiley Online Library
Developing electronic skins (e‐skins) that are comparable to or even beyond human tactile
perception holds significant importance in advancing the process of intellectualization. In …

Usher syndrome: genetics of a human ciliopathy

C Fuster-García, B García-Bohórquez… - International journal of …, 2021 - mdpi.com
Usher syndrome (USH) is an autosomal recessive syndromic ciliopathy characterized by
sensorineural hearing loss, retinitis pigmentosa and, sometimes, vestibular dysfunction …

[HTML][HTML] Physics of mechanotransduction by Piezo ion channels

M Young, AH Lewis, J Grandl - Journal of General Physiology, 2022 - rupress.org
Piezo ion channels are sensors of mechanical forces and mediate a wide range of
physiological mechanotransduction processes. More than a decade of intense research has …