Cellular differentiation, mating, and filamentous growth are regulated in many fungi by
environmental and nutritional signals. For example, in response to nitrogen limitation …

Candida albicans is an opportunistic fungal pathogen that is found in the normal
gastrointestinal flora of most healthy humans. However, under certain environmental …

Cryptococcus gattii causes life-threatening infection of the pulmonary and central nervous
systems in hosts with normal immunity and traditionally has been considered to be restricted …

Many fungi undergo a developmental transition from a unicellular yeast form to an invasive
filamentous form in response to environmental cues. Here we describe a quorum signaling …

Sex is shrouded in mystery. Not only does it preferentially occur in the dark for both fungi
and many animals, but evolutionary biologists continue to debate its benefits given costs in …

Cryptococcosis is an infectious disease caused by pathogenic encapsulated yeasts in the
genus Cryptococcus. Currently, two species of these fungi commonly cause disease in …

Cryptococcus neoformans is a major cause of fungal meningoencephalitis in
immunocompromised patients. Despite recent advances in the genetics and molecular …

Cryptococcus neoformans and Cryptococcus gattii are closely related pathogenic fungi that
cause pneumonia and meningitis in both immunocompromised and immunocompetent …

Genealogy can illuminate the evolutionary path of important human pathogens. In some
microbes, strict clonal reproduction predominates, as with the worldwide dissemination of …

Cryptococcus neoformans strains classically have been grouped into two varieties that
included five serotypes known as C. neoformans variety neoformans (serotypes A, D, and …