Keloids are pathological scars that grow over time and extend beyond the initial site of injury
after impaired wound healing. These scars frequently recur and rarely regress. They are …

Background: Keloid management can be difficult and frustrating, and the mechanisms
underlying keloid formation are only partially understood. Methods: Using original and …

Calcium has an established role in the normal homeostasis of mammalian skin and serves
as a modulator in keratinocyte proliferation and differentiation. Gradients of calcium …

Keloids and scars: a review of keloids and scars, their path... : Current Opinion in Pediatrics
Keloids and scars: a review of keloids and scars, their pathogenesis, risk factors, and …

Background. Keloids and hypertrophic scars are benign fibrous growths that occur after
trauma or wounding of the skin and present a major therapeutic dilemma to the …

Since their earliest description, keloids and hypertrophic scars have beleaguered patients
and clinicians alike. These scars can be aesthetically disfiguring, functionally debilitating …

The identification of a gain-of-function mutation in CACNA1C as the cause of Timothy
syndrome, a rare disorder characterized by cardiac arrhythmias and syndactyly, highlighted …

Keloids and hypertrophic scars represent exuberant forms of scar formation that frequently
are pruritic, painful, and occasionally form strictures. As well, they may result in significant …

BACKGROUND Although differing in clinical presentation and prognosis, keloids and
hypertrophic scars are generally characterized by abnormally proliferative scar tissue and …

Objectives. Multiple conservative therapies for the treatment of Peyronie's disease have
been offered with variable and poor response rates. Calcium channel blockers have been …