Mitochondrial transfer/transplantation: an emerging therapeutic approach for multiple diseases
Z Liu, Y Sun, Z Qi, L Cao, S Ding - Cell & bioscience, 2022 - Springer
Mitochondria play a pivotal role in energy generation and cellular physiological processes.
These organelles are highly dynamic, constantly changing their morphology, cellular …
These organelles are highly dynamic, constantly changing their morphology, cellular …
Mitochondrial function in development and disease
MP Rossmann, SM Dubois… - Disease models & …, 2021 - journals.biologists.com
Mitochondria are organelles with vital functions in almost all eukaryotic cells. Often
described as the cellular 'powerhouses' due to their essential role in aerobic oxidative …
described as the cellular 'powerhouses' due to their essential role in aerobic oxidative …
[HTML][HTML] Inter and intracellular mitochondrial transfer: Future of mitochondrial transplant therapy in Parkinson's disease
R Jain, N Begum, KP Tryphena, SB Singh… - Biomedicine & …, 2023 - Elsevier
Parkinson's disease (PD) is marked by the gradual degeneration of dopaminergic neurons
and the intracellular build-up of Lewy bodies rich in α-synuclein protein. This impairs various …
and the intracellular build-up of Lewy bodies rich in α-synuclein protein. This impairs various …
Mitochondrial transfer as a novel therapeutic approach in disease diagnosis and treatment
VJ Clemente-Suárez, A Martín-Rodríguez… - International Journal of …, 2023 - mdpi.com
Mitochondrial dysfunction is a hallmark of numerous diseases, including neurodegenerative
disorders, metabolic disorders, and cancer. Mitochondrial transfer, the transfer of …
disorders, metabolic disorders, and cancer. Mitochondrial transfer, the transfer of …
Muscle mitochondrial transplantation can rescue and maintain cellular homeostasis
D Bhattacharya, MB Slavin… - American Journal of …, 2023 - journals.physiology.org
Mitochondria control cellular functions through their metabolic role. Recent research that has
gained considerable attention is their ability to transfer between cells. This has the potential …
gained considerable attention is their ability to transfer between cells. This has the potential …
Mitochondrial dysfunction and skeletal muscle atrophy: Causes, mechanisms, and treatment strategies
Skeletal muscle, which accounts for approximately 40% of total body weight, is one of the
most dynamic and plastic tissues in the human body and plays a vital role in movement …
most dynamic and plastic tissues in the human body and plays a vital role in movement …
Mitochondrial transplantation attenuates cerebral ischemia‐reperfusion injury: possible involvement of mitochondrial component separation
Q Xie, J Zeng, Y Zheng, T Li, J Ren… - Oxidative Medicine …, 2021 - Wiley Online Library
Background. Mitochondrial dysfunctions play a pivotal role in cerebral ischemia‐reperfusion
(I/R) injury. Although mitochondrial transplantation has been recently explored for the …
(I/R) injury. Although mitochondrial transplantation has been recently explored for the …
Perspectives on mitochondrial relevance in cardiac ischemia/reperfusion injury
Cardiovascular disease is the most common cause of death worldwide and in particular,
ischemic heart disease holds the most considerable position. Even if it has been deeply …
ischemic heart disease holds the most considerable position. Even if it has been deeply …
Mitochondrial transplantation therapy for ischemia reperfusion injury: a systematic review of animal and human studies
K Hayashida, R Takegawa, M Shoaib, T Aoki… - Journal of Translational …, 2021 - Springer
Background Mitochondria are essential organelles that provide energy for cellular functions,
participate in cellular signaling and growth, and facilitate cell death. Based on their …
participate in cellular signaling and growth, and facilitate cell death. Based on their …
Mitochondrial transplantation for organ rescue
JD McCully, PJ Del Nido, SM Emani - Mitochondrion, 2022 - Elsevier
Mitochondrial transplantation involves the replacement or augmentation of native
mitochondria damaged, by ischemia, with viable, respiration-competent mitochondria …
mitochondria damaged, by ischemia, with viable, respiration-competent mitochondria …