Astrocyte endfeet in brain function and pathology: open questions
Astrocyte endfeet enwrap the entire vascular tree within the central nervous system, where
they perform important functions in regulating the blood-brain barrier (BBB), cerebral blood …
they perform important functions in regulating the blood-brain barrier (BBB), cerebral blood …
Physiology of astroglia
A Verkhratsky, M Nedergaard - Physiological reviews, 2018 - journals.physiology.org
Astrocytes are neural cells of ectodermal, neuroepithelial origin that provide for homeostasis
and defense of the central nervous system (CNS). Astrocytes are highly heterogeneous in …
and defense of the central nervous system (CNS). Astrocytes are highly heterogeneous in …
Astrocytes in chronic pain and itch
Astrocytes are critical for maintaining the homeostasis of the CNS. Increasing evidence
suggests that a number of neurological and neuropsychiatric disorders, including chronic …
suggests that a number of neurological and neuropsychiatric disorders, including chronic …
[HTML][HTML] Behaviorally consequential astrocytic regulation of neural circuits
Astrocytes are a large and diverse population of morphologically complex cells that exist
throughout nervous systems of multiple species. Progress over the last two decades has …
throughout nervous systems of multiple species. Progress over the last two decades has …
[HTML][HTML] Cell biology of astrocyte-synapse interactions
Astrocytes, the most abundant glial cells in the mammalian brain, are critical regulators of
brain development and physiology through dynamic and often bidirectional interactions with …
brain development and physiology through dynamic and often bidirectional interactions with …
Neuron–glia interactions in the pathophysiology of epilepsy
Epilepsy is a neurological disorder afflicting~ 65 million people worldwide. It is caused by
aberrant synchronized firing of populations of neurons primarily due to imbalance between …
aberrant synchronized firing of populations of neurons primarily due to imbalance between …
Astroglial Kir4. 1 in the lateral habenula drives neuronal bursts in depression
Y Cui, Y Yang, Z Ni, Y Dong, G Cai, A Foncelle, S Ma… - Nature, 2018 - nature.com
Enhanced bursting activity of neurons in the lateral habenula (LHb) is essential in driving
depression-like behaviours, but the cause of this increase has been unknown. Here, using a …
depression-like behaviours, but the cause of this increase has been unknown. Here, using a …
Astrocyte-immune cell interactions in physiology and pathology
Astrocytes play both physiological and pathological roles in maintaining central nervous
system (CNS) function. Here, we review the varied functions of astrocytes and how these …
system (CNS) function. Here, we review the varied functions of astrocytes and how these …
Differentiation and maturation of oligodendrocytes in human three-dimensional neural cultures
Investigating human oligodendrogenesis and the interaction of oligodendrocytes with
neurons and astrocytes would accelerate our understanding of the mechanisms underlying …
neurons and astrocytes would accelerate our understanding of the mechanisms underlying …
Going the extra (synaptic) mile: excitotoxicity as the road toward neurodegenerative diseases
A Armada-Moreira, JI Gomes, CC Pina… - Frontiers in cellular …, 2020 - frontiersin.org
Excitotoxicity is a phenomenon that describes the toxic actions of excitatory
neurotransmitters, primarily glutamate, where the exacerbated or prolonged activation of …
neurotransmitters, primarily glutamate, where the exacerbated or prolonged activation of …