[HTML][HTML] Advances in oral nano-delivery systems for colon targeted drug delivery in inflammatory bowel disease: selective targeting to diseased versus healthy tissue
Colon targeted drug delivery is an active area of research for local diseases affecting the
colon, as it improves the efficacy of therapeutics and enables localized treatment, which …
colon, as it improves the efficacy of therapeutics and enables localized treatment, which …
Oral nanomedicine for modulating immunity, intestinal barrier functions, and gut microbiome
The gastrointestinal tract (GIT) affects not only local diseases in the GIT but also various
systemic diseases. Factors that can affect the health and disease of both GIT and the human …
systemic diseases. Factors that can affect the health and disease of both GIT and the human …
Biomimetic MOF nanoparticles delivery of C-dot nanozyme and CRISPR/Cas9 system for site-specific treatment of ulcerative colitis
Y Ma, W Gao, Y Zhang, M Yang, X Yan… - … Applied Materials & …, 2022 - ACS Publications
Ulcerative colitis (UC) is a chronic inflammatory bowel disease (IBD) of unknown etiology
affecting the colon and rectum. Previous studies have found that reactive oxygen species …
affecting the colon and rectum. Previous studies have found that reactive oxygen species …
Oral administration of ginger-derived nanolipids loaded with siRNA as a novel approach for efficient siRNA drug delivery to treat ulcerative colitis
Aim: To develop novel siRNA delivery system overcoming the limitations of synthetic
nanoparticles, such as potential side effects, nonspecificity and economic production for …
nanoparticles, such as potential side effects, nonspecificity and economic production for …
A superoxide dismutase/catalase mimetic nanomedicine for targeted therapy of inflammatory bowel disease
Oxidative stress, resulting from excessive generation of reactive oxygen species (ROS),
plays a pivotal role in the initiation and progression of inflammatory bowel disease (IBD). To …
plays a pivotal role in the initiation and progression of inflammatory bowel disease (IBD). To …
[HTML][HTML] Combination therapy for ulcerative colitis: orally targeted nanoparticles prevent mucosal damage and relieve inflammation
Combination therapy is an emerging strategy that is under intensive preclinical investigation
for the treatment of various diseases. CD98 is highly overexpressed on the surfaces of …
for the treatment of various diseases. CD98 is highly overexpressed on the surfaces of …
Nanoparticles with surface antibody against CD98 and carrying CD98 small interfering RNA reduce colitis in mice
Background & Aims Nanoparticles have been explored as carriers of small interfering RNAs
(siRNAs) and might be developed to treat patients with inflammatory bowel disease (IBD) …
(siRNAs) and might be developed to treat patients with inflammatory bowel disease (IBD) …
[HTML][HTML] Insights from advances in research of chemically induced experimental models of human inflammatory bowel disease
M Kawada, A Arihiro, E Mizoguchi - World journal of …, 2007 - ncbi.nlm.nih.gov
Inflammatory bowel disease (IBD), the most important being Crohn's disease and ulcerative
colitis, results from chronic dysregulation of the mucosal immune system in the …
colitis, results from chronic dysregulation of the mucosal immune system in the …
Natural product-based nanomedicine in treatment of inflammatory bowel disease
Many synthetic drugs and monoclonal antibodies are currently in use to treat Inflammatory
Bowel Disease (IBD). However, they all are implicated in causing severe side effects and …
Bowel Disease (IBD). However, they all are implicated in causing severe side effects and …
Inflammatory bowel disease: exploring gut pathophysiology for novel therapeutic targets
V Yadav, F Varum, R Bravo, E Furrer, D Bojic… - Translational …, 2016 - Elsevier
Ulcerative colitis and Crohn's disease are the 2 major phenotypes of inflammatory bowel
disease (IBD), which are influenced by a complex interplay of immunological and genetic …
disease (IBD), which are influenced by a complex interplay of immunological and genetic …