ROS from physical plasmas: Redox chemistry for biomedical therapy

A Privat-Maldonado, A Schmidt, A Lin… - Oxidative medicine …, 2019 - Wiley Online Library
Physical plasmas generate unique mixes of reactive oxygen and nitrogen species (RONS or
ROS). Only a bit more than a decade ago, these plasmas, operating at body temperature …

The emerging role of gas plasma in oncotherapy

X Dai, K Bazaka, DJ Richard, ERW Thompson… - Trends in …, 2018 - cell.com
Atmospheric pressure gas plasmas are emerging as a promising treatment in cancer that
can supplement the existing set of treatment modalities and, when combined with other …

Non-thermal plasma-treated solution demonstrates antitumor activity against pancreatic cancer cells in vitro and in vivo

KR Liedtke, S Bekeschus, A Kaeding, C Hackbarth… - Scientific reports, 2017 - nature.com
Pancreatic cancer is associated with a high mortality rate. In advanced stage, patients often
experience peritoneal carcinomatosis. Using a syngeneic murine pancreatic cancer cell …

Cold atmospheric plasma induces GSDME-dependent pyroptotic signaling pathway via ROS generation in tumor cells

X Yang, G Chen, KN Yu, M Yang, S Peng, J Ma… - Cell death & …, 2020 - nature.com
Cold atmospheric plasma (CAP) has been proposed as a novel promising anti-cancer
treatment modality. Apoptosis and necrosis have been revealed in CAP-induced cell death …

Combination of chemotherapy and physical plasma elicits melanoma cell death via upregulation of SLC22A16

SK Sagwal, G Pasqual-Melo, Y Bodnar… - Cell Death & …, 2018 - nature.com
Malignant melanoma is an aggressive cancer that develops drug resistance leading to poor
prognosis. Efficient delivery of chemotherapeutic drugs to the tumor tissue remains a major …

Combination therapy of cold atmospheric plasma (CAP) with temozolomide in the treatment of U87MG glioblastoma cells

E Gjika, S Pal-Ghosh, ME Kirschner, L Lin… - Scientific Reports, 2020 - nature.com
Cold atmospheric plasma (CAP) technology, a relatively novel technique mainly
investigated as a stand-alone cancer treatment method in vivo and in vitro, is being …

Intraperitoneal administration of plasma-activated medium: proposal of a novel treatment option for peritoneal metastasis from gastric cancer

S Takeda, S Yamada, N Hattori, K Nakamura… - Annals of surgical …, 2017 - Springer
Background The administration of fluid irradiated with non-equilibrium atmospheric pressure
plasma (NEAPP) has attracted much interest as a novel therapeutic method for cancer. The …

Non-thermal atmospheric plasma induces ROS-independent cell death in U373MG glioma cells and augments the cytotoxicity of temozolomide

GE Conway, A Casey, V Milosavljevic, Y Liu… - British journal of …, 2016 - nature.com
Background: Non-thermal atmospheric plasma (NTAP) is an ionised gas produced under
high voltage that can generate short-lived chemically active species and induce a cytotoxic …

Physical plasma elicits immunogenic cancer cell death and mitochondrial singlet oxygen

S Bekeschus, A Mueller, V Miller… - … on Radiation and …, 2017 - ieeexplore.ieee.org
Plasma oncotherapy receives increasing attention due to considerable success in
preclinical research. Different plasma sources were shown to induce cancer cell death in …

Cold atmospheric plasma attenuates breast cancer cell growth through regulation of cell microenvironment effectors

CA Aggelopoulos, AM Christodoulou… - Frontiers in …, 2022 - frontiersin.org
Breast cancer exists in multiple subtypes some of which still lack a targeted and effective
therapy. Cold atmospheric plasma (CAP) has been proposed as an emerging anti-cancer …