Total-body PET: maximizing sensitivity to create new opportunities for clinical research and patient care

SR Cherry, T Jones, JS Karp, J Qi… - Journal of Nuclear …, 2018 - Soc Nuclear Med
PET is widely considered the most sensitive technique available for noninvasively studying
physiology, metabolism, and molecular pathways in the living human being. However, the …

Dynamic whole-body PET imaging: principles, potentials and applications

A Rahmim, MA Lodge, NA Karakatsanis… - European journal of …, 2019 - Springer
Purpose In this article, we discuss dynamic whole-body (DWB) positron emission
tomography (PET) as an imaging tool with significant clinical potential, in relation to …

Iterative PET image reconstruction using convolutional neural network representation

K Gong, J Guan, K Kim, X Zhang, J Yang… - IEEE transactions on …, 2018 - ieeexplore.ieee.org
PET image reconstruction is challenging due to the ill-poseness of the inverse problem and
limited number of detected photons. Recently, the deep neural networks have been widely …

First results on kinetic modelling and parametric imaging of dynamic 18F-FDG datasets from a long axial FOV PET scanner in oncological patients

H Sari, C Mingels, I Alberts, J Hu, D Buesser… - European journal of …, 2022 - Springer
Purpose To investigate the kinetics of 18 F-fluorodeoxyglucose (18 F-FDG) by positron
emission tomography (PET) in multiple organs and test the feasibility of total-body …

[HTML][HTML] Kinetic modeling and parametric imaging with dynamic PET for oncological applications: general considerations, current clinical applications, and future …

A Dimitrakopoulou-Strauss, L Pan… - European journal of …, 2021 - Springer
Dynamic PET (dPET) studies have been used until now primarily within research purposes.
Although it is generally accepted that the information provided by dPET is superior to that of …

The impact of image reconstruction settings on 18F-FDG PET radiomic features: multi-scanner phantom and patient studies

I Shiri, A Rahmim, P Ghaffarian, P Geramifar… - European …, 2017 - Springer
Objectives The purpose of this study was to investigate the robustness of different PET/CT
image radiomic features over a wide range of different reconstruction settings. Methods …

PET parametric imaging: past, present, and future

G Wang, A Rahmim, RN Gunn - IEEE transactions on radiation …, 2020 - ieeexplore.ieee.org
Positron emission tomography (PET) is actively used in a diverse range of applications in
oncology, cardiology, and neurology. The use of PET in the clinical setting focuses on static …

Total-body PET multiparametric imaging of cancer using a voxelwise strategy of compartmental modeling

G Wang, L Nardo, M Parikh… - Journal of Nuclear …, 2022 - Soc Nuclear Med
Quantitative dynamic PET with compartmental modeling has the potential to enable
multiparametric imaging and more accurate quantification than static PET imaging …

Ultra-low-activity total-body dynamic PET imaging allows equal performance to full-activity PET imaging for investigating kinetic metrics of 18F-FDG in healthy …

G Liu, P Hu, H Yu, H Tan, Y Zhang, H Yin, Y Hu… - European journal of …, 2021 - Springer
Purpose To investigate the feasibility of ultra-low-activity total-body positron emission
tomography (PET) dynamic imaging for quantifying kinetic metrics of 2-[18 F]-fluoro-2-deoxy …

[HTML][HTML] Advantages and applications of total-body PET scanning

S Katal, LS Eibschutz, B Saboury… - Diagnostics, 2022 - mdpi.com
Recent studies have focused on the development of total-body PET scanning in a variety of
fields such as clinical oncology, cardiology, personalized medicine, drug development and …