The endogenous cannabinoid transmitter system regulates synaptic transmission
throughout the nervous system. Unlike conventional transmitters, specific stimuli induce …

Astrocytes are emerging as key regulators of cognitive function and behavior. This review
highlights some of the latest advances in the understanding of astrocyte roles in different …

Experience-dependent expression of immediate-early gene transcription factors (IEG-TFs)
can transiently change the transcriptome of active neurons and initiate persistent changes in …

Highlights•Endocannabinoids (eCBs) are powerful modulators of inhibitory synaptic
transmission.•eCBs control inhibitory synapses in an activity-dependent (ie phasic) or tonic …

While chronic stress induces dendritic atrophy in the hippocampus and impairs learning and
memory, supplementation with n-3 polyunsaturated fatty acids (n-3 PUFA) is known to …

Many neurodevelopmental and neuropsychiatric disorders involve an imbalance between
excitation and inhibition caused by synaptic alterations. The proper excitation/inhibition (E/I) …

Endocannabinoid (eCB)–mediated suppression of inhibitory synapses has been
hypothesized, but this has not yet been demonstrated to occur in vivo because of the …

The cortex encodes a broad range of inputs. This breadth of operation requires sensitivity to
weak inputs yet non-saturating responses to strong inputs. If individual pyramidal neurons …

Background Multifractal analysis quantifies the time-scale-invariant properties in data by
describing the structure of variability over time. By applying this analysis to hippocampal …

Feed-forward inhibition is vital in the transfer and processing of synaptic information within
the hippocampal–entorhinal loop by controlling the strength and direction of excitation flow …