The role of bioactive compounds in natural products extracted from plants in cancer treatment and their mechanisms related to anticancer effects
M Yuan, G Zhang, W Bai, X Han, C Li… - Oxidative Medicine and …, 2022 - Wiley Online Library
Cancer is one of the greatest causes of death worldwide. With the development of surgery,
radiotherapy, and medical agents, the outcomes of cancer patients have greatly improved …
radiotherapy, and medical agents, the outcomes of cancer patients have greatly improved …
Melatonin as a regulator of apoptosis in leukaemia: molecular mechanism and therapeutic perspectives
A Mafi, H Rismanchi, Y Gholinezhad… - Frontiers in …, 2023 - frontiersin.org
Leukaemia is a dangerous malignancy that causes thousands of deaths every year
throughout the world. The rate of morbidity and mortality is significant despite many …
throughout the world. The rate of morbidity and mortality is significant despite many …
Melatonin: new insights on its therapeutic properties in diabetic complications
MH Pourhanifeh, A Hosseinzadeh… - Diabetology & metabolic …, 2020 - Springer
Diabetes and diabetic complications are considered as leading causes of both morbidity
and mortality in the world. Unfortunately, routine medical treatments used for affected …
and mortality in the world. Unfortunately, routine medical treatments used for affected …
Melatonin, an ubiquitous metabolic regulator: functions, mechanisms and effects on circadian disruption and degenerative diseases
The last four decades, we assist to an increasing scientific interest on melatonin, a circadian
hormone, a metabolic regulator which influences not only plants' metabolism and their …
hormone, a metabolic regulator which influences not only plants' metabolism and their …
Targeting cancer stem cells by melatonin: Effective therapy for cancer treatment
Melatonin is a physiological hormone produced by the pineal gland. In recent decades,
enormous investigations showed that melatonin can prompt apoptosis in cancer cells and …
enormous investigations showed that melatonin can prompt apoptosis in cancer cells and …
In vitro and in vivo anticancer effects of syringic acid on colorectal cancer: Possible mechanistic view
A Mihanfar, SG Darband, S Sadighparvar… - Chemico-Biological …, 2021 - Elsevier
This study aimed to evaluate the in vitro effects of syringic acid on human colorectal cancer
cells (SW-480) and the effect of orally administered syringic acid on in vivo models of …
cells (SW-480) and the effect of orally administered syringic acid on in vivo models of …
Melatonin and cancer: A polyhedral network where the source matters
MA Bonmati-Carrion, A Tomas-Loba - Antioxidants, 2021 - mdpi.com
Melatonin is one of the most phylogenetically conserved signals in biology. Although its
original function was probably related to its antioxidant capacity, this indoleamine has been …
original function was probably related to its antioxidant capacity, this indoleamine has been …
Sleep during oncological treatment–a systematic review and meta-analysis of associations with treatment response, time to progression and survival
L Strøm, JT Danielsen, A Amidi… - Frontiers in …, 2022 - frontiersin.org
Introduction Disrupted sleep and sleep-wake activity are frequently observed in cancer
patients undergoing oncological treatment. These disruptions are often associated with …
patients undergoing oncological treatment. These disruptions are often associated with …
Melatonin and gastrointestinal cancers: Current evidence based on underlying signaling pathways
Gastrointestinal (GI) cancers, leading causes of cancer-related deaths, have been serious
challenging human diseases up to now. Because of high rates of mortality, late-stage …
challenging human diseases up to now. Because of high rates of mortality, late-stage …
The role of circadian clock genes in colorectal carcinoma: novel insights into regulatory mechanism and implications in clinical therapy
H Zhu, J Chen, Z Wen, J Li, Q Yu, W Liao, X Luo - Life Sciences, 2023 - Elsevier
Colorectal cancer (CRC) is a lethal malignancy with limited treatment strategies.
Accumulating evidence indicates that CRC tumorigenesis, progression and metastasis are …
Accumulating evidence indicates that CRC tumorigenesis, progression and metastasis are …