'Magnesium'-the master cation-as a drug—possibilities and evidences

AA Mathew, R Panonnummal - Biometals, 2021 - Springer
Abstract Magnesium (Mg2+) is the 2nd most abundant intracellular cation, which participates
in various enzymatic reactions; there by regulating vital biological functions. Magnesium …

The role of magnesium in pathophysiology and migraine treatment

S Dolati, R Rikhtegar, A Mehdizadeh… - Biological trace element …, 2020 - Springer
Migraine is one of the most common recurrent types of headache and is the seventh cause
of disability. This neurological disorder is characterized by having pain in head and other …

Skin minerals: key roles of inorganic elements in skin physiological functions

M Haftek, R Abdayem… - International Journal of …, 2022 - mdpi.com
As odd as it may seem at first glance, minerals, it is what we are all about… or nearly.
Although life on Earth is carbon-based, several other elements present in the planet's crust …

Magnesium: The overlooked electrolyte in blood cancers?

J Gile, G Ruan, J Abeykoon, MM McMahon, T Witzig - Blood reviews, 2020 - Elsevier
Magnesium is an important element that has essential roles in the regulation of cell growth,
division, and differentiation. Mounting evidence in the literature suggests an association …

Myth or reality—transdermal magnesium?

U Gröber, T Werner, J Vormann, K Kisters - Nutrients, 2017 - mdpi.com
In the following review, we evaluated the current literature and evidence-based data on
transdermal magnesium application and show that the propagation of transdermal …

Development of a two-dimensional model for predicting transdermal permeation with the follicular pathway: demonstration with a caffeine study

P Kattou, G Lian, S Glavin, I Sorrell, T Chen - Pharmaceutical research, 2017 - Springer
Purpose The development of a new two-dimensional (2D) model to predict follicular
permeation, with integration into a recently reported multi-scale model of transdermal …

Influence of nanocrystal size on the in vivo absorption kinetics of caffeine after topical application

P Breuckmann, MC Meinke, T Jaenicke… - European Journal of …, 2021 - Elsevier
The absorption of topically applied substances is challenging due to the effective skin
barrier. Encapsulation of substances into nanoparticles was expected to be promising to …

Inorganic ions in the skin: Allies or enemies?

M Tarnowska, S Briancon, JR de Azevedo… - International Journal of …, 2020 - Elsevier
Skin constitutes a barrier protecting the organism against physical and chemical factors.
Therefore, it is constantly exposed to the xenobiotics, including inorganic ions that are …

Hair Follicle-Targeted Delivery of Azelaic Acid Micro/Nanocrystals Promote the Treatment of Acne Vulgaris

Y Ji, H Li, J Li, G Yang, W Zhang, Y Shen… - International Journal …, 2024 - Taylor & Francis
Purpose Acne vulgaris is a chronic inflammatory skin disorder centered on hair follicles,
making hair follicle-targeted delivery of anti-acne drugs a promising option for acne …

The effect of vehicle on skin absorption of Mg2+ and Ca2+ from thermal spring water

M Tarnowska, S Briançon… - … Journal of Cosmetic …, 2020 - Wiley Online Library
Objective Thermal spring waters (TSW) are commonly used as active ingredients in
cosmetics. Their biological activities directly depend on the ionic composition of the spring …