Role of sleep deprivation in immune-related disease risk and outcomes

S Garbarino, P Lanteri, NL Bragazzi… - Communications …, 2021 - nature.com
Modern societies are experiencing an increasing trend of reduced sleep duration, with
nocturnal sleeping time below the recommended ranges for health. Epidemiological and …

Targeting early atherosclerosis: a focus on oxidative stress and inflammation

P Marchio, S Guerra-Ojeda, JM Vila… - Oxidative medicine …, 2019 - Wiley Online Library
Atherosclerosis is a chronic vascular inflammatory disease associated to oxidative stress
and endothelial dysfunction. Oxidation of low‐density lipoprotein (LDL) cholesterol is one of …

[HTML][HTML] The role of vascular biomarkers for primary and secondary prevention. A position paper from the European Society of Cardiology Working Group on …

C Vlachopoulos, P Xaplanteris, V Aboyans… - Atherosclerosis, 2015 - Elsevier
While risk scores are invaluable tools for adapted preventive strategies, a significant gap
exists between predicted and actual event rates. Additional tools to further stratify the risk of …

C-reactive protein in atherothrombosis and angiogenesis

L Badimon, E Peña, G Arderiu, T Padró… - Frontiers in …, 2018 - frontiersin.org
C-reactive protein (CRP) is a short pentraxin mainly found as a pentamer in the circulation,
or as non-soluble monomers CRP (mCRP) in tissues, exerting different functions. This …

Coronary artery disease in patients≥ 80 years of age

MV Madhavan, BJ Gersh, KP Alexander… - Journal of the American …, 2018 - jacc.org
Coronary artery disease (CAD) is a major cause of morbidity and mortality in patients≥ 80
years of age. Nonetheless, older patients have typically been under-represented in …

Role of coronary artery calcium score of zero and other negative risk markers for cardiovascular disease: the Multi-Ethnic Study of Atherosclerosis (MESA)

MJ Blaha, M Cainzos-Achirica, P Greenland… - Circulation, 2016 - Am Heart Assoc
Background—Limited attention has been paid to negative cardiovascular disease (CVD) risk
markers despite their potential to improve medical decision making. We compared 13 …

A test in context: high-sensitivity C-reactive protein

PM Ridker - Journal of the American College of Cardiology, 2016 - jacc.org
The inflammatory biomarker high-sensitivity C-reactive protein (hsCRP) adds prognostic
information on cardiovascular risk comparable to blood pressure or cholesterol. Values< 1, 1 …

[HTML][HTML] IgG glycans in health and disease: Prediction, intervention, prognosis, and therapy

S Shkunnikova, A Mijakovac, L Sironic, M Hanic… - Biotechnology …, 2023 - Elsevier
Immunoglobulin (IgG) glycosylation is a complex enzymatically controlled process, essential
for the structure and function of IgG. IgG glycome is relatively stable in the state of …

Colchicine therapy and plaque stabilization in patients with acute coronary syndrome: a CT coronary angiography study

K Vaidya, C Arnott, GJ Martínez, B Ng… - JACC: Cardiovascular …, 2018 - jacc.org
Objectives: The authors sought to evaluate the plaque-modifying effects of low-dose
colchicine therapy plus optimal medical therapy (OMT) in patients post-acute coronary …

C-reactive protein: a target for therapy to reduce inflammation

SA Rizo-Téllez, M Sekheri, JG Filep - Frontiers in immunology, 2023 - frontiersin.org
C-reactive protein (CRP) is well-recognized as a sensitive biomarker of inflammation.
Association of elevations in plasma/serum CRP level with disease state has received …